Results 41 to 50 of about 3,273,373 (295)

On the Impact of the Fabrication Method on the Performance of 3D Printed Mixers

open access: yesMicromachines, 2019
A wide variety of 3D printing technologies have been used for the fabrication of lab-on-a-chip (LOC) devices in recent years. Despite the large number of studies having examined the use of 3D printing technologies in microfluidic devices, the effect of ...
Mojtaba Zeraatkar   +2 more
doaj   +1 more source

A Neuroevolutionary Model to Estimate the Tensile Strength of Manufactured Parts Made by 3D Printing

open access: yesAlgorithms, 2022
Three-dimensional printing has advantages, such as an excellent flexibility in producing parts from the digital model, enabling the fabrication of different geometries that are both simple or complex, using low-cost materials and generating little ...
Matheus Alencar da Silva   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A COMPARISON OF THE TENSILE STRENGTH OF PLASTIC PARTS PRODUCED BY A FUSED DEPOSITION MODELING DEVICE

open access: yesActa Polytechnica, 2015
Rapid Prototyping systems are nowadays increasingly used in many areas of industry, not only for producing design models but also for producing parts for final use. We need to know the properties of these parts.
Juraj Beniak   +2 more
doaj   +1 more source

Properties of oriented carbon fiber/polyamide 12 composite parts fabricated by fused deposition modeling

open access: yes, 2018
This paper reports the thermal and mechanical properties of carbon fiber (CF) reinforced polyamide 12 (PA12) composites for fused deposition modeling (FDM) process. The printable filaments of carbon fiber/PA12 composites with different mass fraction were
Zhixiang Li   +19 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Biodegradable Poly(Lactic Acid) Nanocomposites for Fused Deposition Modeling 3D Printing

open access: yesNanomaterials, 2020
3D printing by fused deposition modelling (FDM) enables rapid prototyping and fabrication of parts with complex geometries. Unfortunately, most materials suitable for FDM 3D printing are non-degradable, petroleum-based polymers.
Madison Bardot, Michael D. Schulz
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

High-resolution fused deposition 3D printing based on electric-field-driven jet

open access: yes工程科学学报, 2019
The existing fused deposition modeling (FDM) technique faces disadvantages of low resolution and limited printable materials; meanwhile the E-jet-based fused deposition method confronts limitations associated with the formation height, material type ...
ZHAO Jia-wei   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy