Results 51 to 60 of about 3,273,373 (295)

Effect of using 3D-printed shell structure for reinforcement of ultra-high-performance concrete

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2023
This study aims to investigate the effect of 3D-printed polymer shell reinforcemen ton ultra-high-performance concrete. The mechanical properties of ultra-high-performance polymer reinforced concrete have been investigated. At first, the 3D-printed shell
Mohammad Hematibahar   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Multi-responsive shape memory polymer printed by fused deposition modeling technique

open access: yeseXPRESS Polymer Letters, 2020
With the help of three-dimensional (3D) printing technique, complicated and sophisticated structured shape memory polymers (SMPs) devices could be obtained, which have drawn tremendous attention in recent years. However, there is technical limitation for
J. Liu   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The effect of different processing, injection molding (IM) and fused deposition modeling (FDM), on the environmental stress cracking (ESC) behavior of filled and unfilled polycarbonate (PC)

open access: yeseXPRESS Polymer Letters, 2021
The effect of crack propagation management by using a fused deposition modeling (FDM) technique on the environmental stress cracking (ESC) behavior of neat polycarbonate (PC) and PC with 1 vol% SiO2 nanocomposites were investigated.
M. Z. Huang, J. Nomai, A. K. Schlarb
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

On the possibility to fabricate ceramics using fused deposition modeling [PDF]

open access: yes, 2020
The paper presents a uniquely designed device that enables controlled manufacturing of semi-fabricated products from thermoplastic ceramic suspensions by fused deposition modeling. Sintering of the products yields ceramics with high strength and hardness.
Zhukov, Ilya A.   +7 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

National Atmospheric Deposition Program 2011 Annual summary [PDF]

open access: yes, 2012
is peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2013-01-29T22:55:31Z No. of bitstreams: 1 2011as.pdf: 4443124 bytes, checksum: 1e2ff568a6e350fe41bba46c81de3531 (MD5)Made available in DSpace on 2013-01-29T22:55:31Z (GMT). No.
National Atmospheric Deposition Program
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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