Results 71 to 80 of about 252,665 (316)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Variable fused deposition modelling - concept design and tool path generation [PDF]

, 2011
Current Fused Deposition Modelling (FDM) techniques use fixed diameter nozzles to deposit a filament of plastic layer by layer. The consequence is that the same small nozzle, essential for fine details, is also used to fill in relatively large volumes ...
Brooks, Hadley Laurence
core  

Investigate the effects of process parameters on material properties and microstructural changes of 3D-printed specimens using fused deposition modelling (FDM)

, 2020
One of the most significant parameters of the Fused Deposition Modelling (FDM) for 3D printing process is the raster angle. In this study, the five different raster angles are used to fabricate the 3D parts using thermoplastic material - polylactic acid (
N. Naveed
semanticscholar   +1 more source

Taguchi S/N and TOPSIS Based Optimization of Fused Deposition Modelling and Vapor Finishing Process for Manufacturing of ABS Plastic Parts

Materials, 2020
Despite several additive manufacturing techniques are commercially available in market, Fused Deposition Modeling (FDM) is increasingly used by researchers and engineers for new product development.
J. Chohan, Raman Kumar, TH Bhatia Singh, S. Singh, Shubham Sharma, Jujhar Singh, Mozammel Mia, D. Pimenov, S. Chattopadhyaya, S. Dwivedi, W. Kapłonek   +10 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Fused Deposition Modelling of Thermoplastic Polymer Nanocomposites: A Critical Review

C
Fused deposition modelling (FDM) has attracted researchers’ interest in myriads of applications. The enhancement of its part using fillers to print nanocomposites is a cutting-edge domain of research.
Taha Sheikh, Kamran Behdinan
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Fused deposition modelling using direct extrusion

Virtual and Physical Prototyping, 2007
In the present work, a process based on the principle of polymer extrusion is developed: the extruder deposition process (EDP). This system uses a screw extruder to deposit the material on a computer-controlled positioning system to build components.
B. V. Reddy, N. V. Reddy, A. Ghosh
openaire   +1 more source

Bioactive composites for bone tissue engineering [PDF]

, 2010
One of the major challenges of bone tissue engineering is the production of a suitable scaffold material. In this review the current composite materials options available are considered covering both the methods of both production and assessing the ...
Tanner, K.E.
core   +1 more source

Comparative study on the perspective towards the benefits and hindrances of implementing building information modelling (BIM) [PDF]

, 2020
Building Information Modelling (BIM) is considered one of the most effective technologies to improve the productivity of the building process. BIM has proven its advantages throughout the building project life cycle.
Al-Ashmori, Yasser Yahya, Ang, Peniel Soon Ern, Yong, Yee Ooi   +2 more
core   +2 more sources