Results 71 to 80 of about 41,540 (298)

Effect of support on printed properties in fused deposition modelling processes

open access: yesVirtual and Physical Prototyping, 2019
Additive manufacturing still suffers from redundant support material usage when printing parts with overhanging features. All the supports will be removed after fabrication, resulting in wasted materials.
Jingchao Jiang, Jingjun Lou, Guobiao Hu
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Investigation of Parameters of Fused Deposition Modelling 3D Prints with Compression Properties

open access: yesAdvances in Materials Science and Engineering, 2022
Three-dimensional (3D) printing has been attracting a great deal of attention in recent years in many application fields, for example, in the aerospace, construction, industry, art, education, protection, security, and medical fields.
Dereje Berihun Sitotaw   +3 more
doaj   +1 more source

Thermal conditions affecting heat transfer in FDM/FFE: a contribution towards the numerical modelling of the process [PDF]

open access: yes, 2015
The performance of parts produced by Free Form Extrusion (FFE), an increasingly popular additive manufacturing technique, depends mainly on their dimensional accuracy, surface quality and mechanical performance.
ASTM Standard, F2792 – 12a   +7 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Rapid Prototyping: Technologies, Materials and Advances

open access: yesArchives of Metallurgy and Materials, 2016
In the context of product development, the term rapid prototyping (RP) is widely used to describe technologies which create physical prototypes directly from digital data.
Dudek P., Rapacz-Kmita A.
doaj   +1 more source

3D printing a transposed design in biopolymer materials using an articulated robot and pellet-based extrusion : a thesis presented in partial fulfilment of the requirements for a degree of Master of Engineering in Mechatronics at Massey University, Albany, New Zealand [PDF]

open access: yes, 2016
The aim of this project was to develop a new method of 3D printing. This method is a mix between Fused Deposition Modelling and freeform printing, using a 6 degree-of-freedom articulated robot and a pellet-based extruder to mix and distribute the ...
Brooks, Byron
core  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Research on Basic Properties of Polymers for Fused Deposition Modelling Technology

open access: yesApplied Sciences
This study investigates the mechanical properties and biocompatibility of eight commercially available filaments tailored for Fused Deposition Modeling (FDM) additive manufacturing.
Dariusz Pyka   +7 more
doaj   +1 more source

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