Results 131 to 139 of about 281,828 (139)

One-Pot Four-Component Coupling Approach to Polyheterocycles: 6H-Furo[3,2-f]pyrrolo[1,2-d][1,4]diazepine.

Journal of Organic Chemistry, 2020
A novel polyheterocyclic chemical space, 6H-furo[3,2-f]pyrrolo[1,2-d][1,4]diazepine, was generated by a one-pot four-component coupling reaction where multiple bonds (three C-C, one C-O, and one C-N) were formed through a domino sequence.
Seok Hyun Yoon, S. Kim, Ikyon Kim
semanticscholar   +1 more source

ChemInform Abstract: Improved Synthesis of 2,3‐Disubstituted Pyridines by Metallation of 2‐Chloropyridine: A Convenient Route to Fused Polyheterocycles.

ChemInform, 1990
AbstractDisubstituted pyridines such as (III) and (VII) are of biological interest.
F. TRECOURT, F. MARSAIS, T. + GUENGOER, G. QUEGUINER   +3 more
openaire   +1 more source

Overview of Synthesis and Pharmacological Importance of Imidazole‐Based Polyheterocycles

ChemistrySelect
Imidazole, a privileged heterocyclic scaffold, is widely incorporated into clinically used drugs and natural products due to its ability to engage in hydrogen bonding, π–π stacking, and coordination with metal ions.
Pragati Kushwaha
semanticscholar   +1 more source

Green Multicomponent‐Click Strategy for One‐Pot Synthesis of Polyheterocyclic Estazolam Aza‐Analogs and Their Symmetrical Polyheterocycles

Asian Journal of Organic Chemistry
A novel one‐pot synthesis of polyheterocyclic compounds (PHCs) incorporating fused 1,5‐disubstituted 1,2,3‐triazole‐1,4‐benzodiazepines (fused 1,5‐Ds‐1,2,3‐T‐1,4‐BZD) bound to 1,5‐disubstituted tetrazoles (1,5‐Ds‐Ts) was developed via Ugi‐azide four ...
Manuel A. Rentería-Gómez, Diana García-García, Alejandro Corona‐Díaz, Rocío Gámez‐Montaño   +3 more
semanticscholar   +1 more source

Ultrasound-assisted diastereoselective green synthesis of spiro-fused-γ-lactams functionalized with an amide bond heterocyclic bioisostere via the Ugi azide/domino process coupled strategy.

Organic and biomolecular chemistry
A series of linked-type 1,5-disubstituted tetrazoles (1,5-DS-Ts) were synthesised via an isocyanide-based multicomponent reaction (IMCR) and used as synthetic platforms to access bound-type polyheterocycles containing an epoxyisoindol-1(6H)-one scaffold ...
David Calderón-Rangel, Ángel Rentería‐Gómez, A. Cruz-Jiménez, Manuel A Rentería Gómez, J. O. Jiménez‐Halla, Rocío Gámez‐Montaño   +5 more
semanticscholar   +1 more source

A Highly Efficient Synthesis of Imidazo-Fused Polyheterocycles via Groebke—Blackburn—Bienayme Reaction Catalyzed by LaCl3·7H2O.

, 2015
Anand H Shinde, Malipatel Srilaxmi, B. Satpathi, D. Sharada   +3 more
semanticscholar   +1 more source

Recent synthetic developments in a powerful imino Diels–Alder reaction (Povarov reaction): application to the synthesis of N-polyheterocycles and related alkaloids

Tetrahedron, 2009
Vladimir V Kouznetsov
exaly  

A Cascade Strategy for 1,7-Fused Indole (Spiro) Polyheterocycles Construction: Pyrrolo[3,2,1-ij]quinolines

Km Roshani, Mohammad Saim Raza, Shivom Chauhan, Nikunj Singh, Rama Krishna Peddinti   +4 more
openaire   +1 more source

Synthesis and conformational analysis of novel naphthoxazine-fused polyheterocycles

exaly