Results 91 to 100 of about 35,689 (156)

Role of Branched‐Chain Amino Acids in Mitigating Osteosarcopenia: An Experimental Study Using Ovariectomised Mice Models

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Osteosarcopenia, characterised by concurrent bone loss and muscle atrophy, presents a significant challenge in aging populations, particularly in postmenopausal women. The current therapeutic options potentially treat bone and muscle loss independently, highlighting the importance of an integrated approach.
Geum‐Hwa Lee   +5 more
wiley   +1 more source

Simulating Federated Learning to Enable Multi‐Hospital Collaboration for Lumbopelvic Alignment Estimation

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
Federated learning (FL) effectively estimates lumbopelvic parameters from multi‐center spinal imaging, matching centralized methods' accuracy while preserving patient privacy, highlighting FL's potential to enhance diagnostic precision and broaden AI‐driven clinical applications in spine care without compromising data confidentiality.
Andrea Cina   +12 more
wiley   +1 more source

Vertebral Growth Modulation Through Periosteal Resection and Fixed Length Deformity Overcorrection: Computational and In Vivo Pilot Study

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
The feasibility of using growth promoting strategies (vertebral periosteal resection and distraction) was investigated via computational and in vivo analysis. Computational analysis demonstrated that there is an increasing mechanical benefit to utilizing concave distraction over convex compression during spinal deformity correction.
Matthew A. Halanski   +10 more
wiley   +1 more source

Age and Spinal Level as Predictors of Lumbar Disc Degeneration in Humans and Mice: A Comparative Analysis

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
Mouse models are commonly used to study IVD degeneration and related neurological conditions that especially impact elder population. However, how well mice replicate human pathology remains unclear. This study compared lumbar IVD degeneration patterns across age and spinal levels in humans and mice.
Ravij Mehta   +19 more
wiley   +1 more source

Reduced Shear Modulus and Altered Lamellar Morphology of the Outer Annulus Fibrosus in Painful Intervertebral Disc Degeneration Compared With Tissue From Non‐Surgical Controls

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
Disc degeneration (DD) results in a mechanically dysfunctional disc through progressive loss of the intervertebral disc's (IVD) highly organized structure. This study measured shear and structure properties of the outer annulus fibrosus in surgical DD and minimally degenerative (non‐DD) donor individuals.
Taylor J. Bader   +11 more
wiley   +1 more source

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