Results 171 to 180 of about 5,926,327 (233)

Fusidic Acid

Reactions Weekly, 2022
Andrew T.A. Nicolson, Ian M. Gould
semanticscholar   +5 more sources

FUSIDIC ACID

The Lancet, 1962
exaly   +6 more sources

Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis.

European journal of medicinal chemistry, 2022
Sepsis is often caused by systemic inflammatory responses. Stimulator of interferon genes (STING) could be a promising treatment target for sepsis. In this study, we report the design and synthesis of a new series of fusidic acid derivatives.
Junjun Long, Tianhao Ying, Lei Zhang, Tao Yu, Jinhui Wu, Yasen Liu, Xiaoli Li, Guoliang You, Leiming Zhang, Y. Bi   +9 more
semanticscholar   +1 more source

Fusidic acid derivatives from the endophytic fungus Acremonium pilosum F47

Journal of Asian natural products research, 2021
Fusidic acid, a representative member of fungal fusidane triterpenoids, has been clinically used as an antibiotic. In the present study, fusidic acid (1), and its known analogs 16-desacetylfusidic acid (2) and 3β,20-dihydroxy-protosta-16,24-dien-29-oic ...
Chuan Tian, Han Gao, Xiaoping Peng, Gang Li, H. Lou   +4 more
semanticscholar   +1 more source

Fusidic Acid (Sodium Fusidate)

1978
This steroid antibiotic derived from Fusidium coccineum fungus is chemically related to cephalosporin P1. The acid forms colourless crystals which are sparingly soluble in water compared with the sodium salt, sodium fusidate, which is highly water soluble.
A. P. Ball, J. A. Gray, J. McM. Murdoch
openaire   +1 more source

A Nanocomposite Dynamic Covalent Cross-Linked Hydrogel Loaded with Fusidic Acid for Treating Antibiotic-Resistant Infected Wounds.

ACS Applied Bio Materials
Methicillin-resistant Staphylococcus aureus (MRSA) is associated with high levels of morbidity and is considered a difficult-to-treat infection, often requiring nonstandard treatment regimens and antibiotics.
Samaneh Toufanian, Jody Mohammed, Erica Winterhelt, Andrew Lofts, Ridhdhi Dave, Brian K. Coombes, T. Hoare   +6 more
semanticscholar   +1 more source

FUSIDIC ACID IN PSORIASIS

The Lancet, 1971
S, Natarajan, P P, Paily
openaire   +4 more sources

Chitosan and phospholipid assisted topical fusidic acid drug delivery in burn wound: Strategies to conquer pharmaceutical and clinical challenges, opportunities and future panorama.

International Journal of Biological Macromolecules, 2020
Burn is the immense public health issue globally. Low and middle income countries face extensive deaths owing to burn injuries. Availability of conventional therapies for burns has always been painful for patients as well as expensive for our health ...
K. Jyoti, Garima Malik, M. Chaudhary, Monika Sharma, M. Goswami, O. Katare, S. B. Singh, Jitender Madan   +7 more
semanticscholar   +1 more source

Drug repurposing: Fusidic acid as a potential inhibitor of M. tuberculosis FtsZ polymerization - Insight from DFT calculations, molecular docking and molecular dynamics simulations.

Tuberculosis, 2020
Filamentous Temperature Sensitive Mutant Z (FtsZ), an important cell division protein in bacteria, has been validated as a potential target for antibiotics development.
Olayinka I. Akinpelu, Monsurat M. Lawal, Hezekiel M. Kumalo, N. Mhlongo   +3 more
semanticscholar   +1 more source

Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity.

Bioorganic & Medicinal Chemistry, 2020
Fusidic acid (FA) is a potent congener of the fusidane triterpenoid class of antibiotics. Structure-activity relationship (SAR) studies suggest the chemical structure of FA is optimal for its antibacterial activity.
Kawaljit Singh, Gurminder Kaur, Petrus Siningu Shanika, G. Dziwornu, John Okombo, K. Chibale   +5 more
semanticscholar   +1 more source