Results 181 to 190 of about 5,926,327 (233)

Investigation of fusidic acid as a chiral selector in capillary electrophoresis

, 2020
In this short communication, we report the use of a steroid antibiotic, Fusidic Acid (Fus), as a novel chiral selector for enantioseparation in capillary electrophoresis (CE).
Qi Zhang, Siru Ren, Song Xue
semanticscholar   +1 more source

Implementation of Simulated Annealing-Support Vector Machine on QSAR Study of Fusidic Acid Derivatives as Anti-Malarial Agent

2020 6th International Conference on Interactive Digital Media (ICIDM), 2020
Malaria is a disease caused by the Plasmodium falciparum parasite and leads to many cases of deaths. Recently, the combination of several drugs has been used to treat this disease. However, the parasite is known to be resistant to the anti-malarial agent.
F. Rahman, K. Lhaksmana, I. Kurniawan
semanticscholar   +1 more source

QSAR Study of Fusidic Acid Derivative as Anti-Malaria Agents by using Artificial Neural Network-Genetic Algorithm

International Conference on Information and Communicatiaon Technology, 2020
Malaria is a disease that caused many adverse effects on humans. Various attempts have been done to find new anti-malarial agents due to the resistance problem of the existing drug.
Hamzah Faisal Azmi, K. Lhaksmana, I. Kurniawan   +2 more
semanticscholar   +1 more source

Identification of fusidic acid resistance in clinical isolates of Staphylococcus pseudintermedius from dogs in Korea.

Veterinary dermatology (Print), 2020
BACKGROUND Staphylococcus pseudintermedius is a major bacterial species associated with canine pyoderma and otitis. Fusidic acid is used to treat skin infections caused by Gram-positive bacteria.
Y. Lim, J. Hyun, Cheol-Yong Hwang
semanticscholar   +1 more source

High‐yield strain of fusidic acid obtained by atmospheric and room temperature plasma mutagenesis and the transcriptional changes involved in improving its production in fungus Fusidium coccineum

Journal of Applied Microbiology, 2020
To obtain the high‐yield strain of fusidic acid, which is produced from fungus Fusidium coccineum and is the only fusidane‐type antibiotic that has been used clinically, and confirm the changes in the transcription levels involved in increasing its ...
W. Huang, X. Ge, Yi Huang, X. Chai, L. Zhang, Y. X. Zhang, L. Deng, C. Liu, H. Xu, J. Gao   +9 more
semanticscholar   +1 more source

Preparation and evaluation of QbD based fusidic acid loaded in situ gel formulations for burn wound treatment

Journal of Drug Delivery Science and Technology, 2019
The purpose of this research was to prepare and evaluate the potential use of in situ gel formulations for dermal delivery of fusidic acid for burn wound treatment.
N. Aksu, Vildan Yozgatlı, M. E. Okur, Ş. Ayla, A. Yoltaş, N. Okur   +5 more
semanticscholar   +1 more source

Analytical Method Development and Determination of Hydrocortisone acetate and Fusidic acid Simultaneously in Cream formulation, by Reversed Phase HPLC.

Biomedical chromotography, 2020
In this study, an accurate, simple, economical, precise, reproducible reversed-phase HPLC method was developed for the estimation of Fusidic acid and Hydrocortisone acetate, according to the ICH guidelines, in a cream formulation.
N. Rasool, Qudsia Kanwal, M. Waseem
semanticscholar   +1 more source

Lipase-sensitive fusidic acid polymeric nanoparticles based hydrogel for on-demand delivery against MRSA-infected burn wounds

Journal of Drug Delivery Science and Technology, 2023
Noor Ullah, Dildar Khan, N. Ahmed, A. Zafar, Kifayattullah Shah, A. ur Rehman   +5 more
semanticscholar   +1 more source

Discovery, synthesis of novel fusidic acid derivatives possessed amino-terminal groups at the 3-hydroxyl position with anticancer activity.

European journal of medicinal chemistry, 2019
A series of novel fusidic acid (FA) derivatives were synthesized and screened for their in vitro cytotoxicity against the Hela, U87, KBV and MKN45 cancer cell lines.
Jingxuan Ni, Mengqi Guo, Yucheng Cao, Lei Lei, Kangli Liu, Bing-hua Wang, Fangfang Lu, Rong Zhai, Xiangwei Gao, Chunhong Yan, Hongbo Wang, Y. Bi   +11 more
semanticscholar   +1 more source

Resistance to fusidic acid

International Journal of Antimicrobial Agents, 1999
Resistance to fusidic acid is determined by a number of mechanisms. The best described are alterations in elongation factor G, which appear in natural mutants that are harboured at low rates in normal populations of staphylococci (10(6) to 10(8)). Altered drug permeability has also been described, and appears to be plasmid-borne.
J, Turnidge, P, Collignon
openaire   +2 more sources