Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents [PDF]
, 2017 A series of novel fusidic acid (FA) derivatives was synthesized by replacing the carboxylic acid group with various ester and amide groups and evaluated in vitro for their antiplasmodial activity against the chloroquine-sensitive NF54 and multidrug ...
Chibale, Kelly +8 more
core +1 more source
Determination of Fusidic Acid Susceptibility of Multidrug-resistant Gonococcal Isolates from China
Infectious Microbes & Diseases, 2019 . The currently recommended gonococcal therapies are rapidly losing efficacy and; therefore, novel options for treatment are urgently required to ensure future treatment remains available.
Fan Yang +2 more
doaj +1 more source
Microbial Oxidation of the Fusidic Acid Side Chain by Cunninghamella echinulata
Molecules, 2018 Biotransformation of fusidic acid (1) was accomplished using a battery of microorganisms including Cunninghamella echinulata NRRL 1382, which converted fusidic acid (1) into three new metabolites 2–4 and the known metabolite 5.
Abdel-Rahim S. Ibrahim +3 more
doaj +1 more source
Fusidic acid resistance through changes in the dynamics of the drug target. [PDF]
Proc Natl Acad Sci U S A, 2020 Significance The World Health Organization has declared antimicrobial resistance one of the greatest threats to human health. Understanding the molecular mechanisms by which bacteria resist the effects of antibiotic therapies is central to understanding ...
Tomlinson JH, Kalverda AP, Calabrese AN.
europepmc +2 more sources
Old World cutaneous leishmaniasis treatment response varies depending on parasite species, geographical location and development of secondary infection [PDF]
, 2019 Background: In the Kingdom of Saudi Arabia (KSA), Leishmania major and L. tropica are the main causative agents of Old World cutaneous leishmaniasis (CL).
Acosta-Serrano, Álvaro +16 more
core +9 more sources
Journal of Infection in Developing Countries, 2022 Introduction: Scabies is caused by Sarcoptes scabiei var hominis, often causing secondary bacterial infections, especially by Streptococcus pyogenes and Staphylococcus aureus.
Aninda Marina +3 more
doaj +1 more source
Dietary-based gut flora modulation against Clostridium difficile onset [PDF]
, 2007 Clostridium difficile infection is a frequent complication of antibiotic therapy in hospitalised patients, which today is attracting more attention than ever and has led to its classification as a 'superbug'.
Gibson, G.R. +2 more
core +1 more source
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward [PDF]
, 2012 Background We describe an outbreak of Bullous Impetigo (BI), caused by a (methicillin susceptible, fusidic acid resistant) Staphylococcus aureus (SA) strain, spa-type t408, at the neonatal and gynaecology ward of the Jeroen Bosch hospital in the ...
Geraats/Peters, K. +9 more
core +3 more sources
Saudi Pharmaceutical Journal, 2020 The objective of the present research was to examine the possible usage of microemulsion based gel for fusidic acid (FA) dermal application as burn wound treatment.
M. E. Okur +7 more
semanticscholar +1 more source
Genomic Analysis of Companion Rabbit Staphylococcus aureus. [PDF]
, 2016 In addition to being an important human pathogen, Staphylococcus aureus is able to cause a variety of infections in numerous other host species. While the S. aureus strains causing infection in several of these hosts have been well characterised, this is
Fisher, Elizabeth A +6 more
core +15 more sources