Bioactivities and Structure-Activity Relationships of Fusidic Acid Derivatives: A Review. [PDF]
Front Pharmacol, 2021 Fusidic acid (FA) is a natural tetracyclic triterpene isolated from fungi, which is clinically used for systemic and local staphylococcal infections, including methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci infections ...
Long J, Ji W, Zhang D, Zhu Y, Bi Y.
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Emergence and spread of a mupirocin-resistant variant of the European epidemic fusidic acid-resistant impetigo clone of Staphylococcus aureus, Belgium, 2013 to 2023. [PDF]
Euro SurveillBackground Antimicrobial resistance to mupirocin and fusidic acid, which are used for treatment of skin infections caused by Staphylococcus aureus, is of concern.
Yin N +8 more
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AAPS PharmSciTech, 2023 The combination of herbal drugs with a topical antibacterial for managing a chronic disease like acne vulgaris has emerged lately to settle side effects and bacterial multidrug resistance.
Raghda Abdel-monem +3 more
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Synthesis of Fusidic Acid Derivatives Yields a Potent Antibiotic with an Improved Resistance Profile. [PDF]
ACS Infect Dis, 2021 Fusidic acid (FA) is a potent steroidal antibiotic that has been used in Europe for more than 60 years to treat a variety of infections caused by Gram-positive pathogens. Despite its clinical success, FA requires significantly elevated dosing (3 g on the
Garcia Chavez M +6 more
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Characterization of two malaria parasite organelle translation elongation factor G proteins: the likely targets of the anti-malarial fusidic acid. [PDF]
PLoS ONE, 2011 Malaria parasites harbour two organelles with bacteria-like metabolic processes that are the targets of many anti-bacterial drugs. One such drug is fusidic acid, which inhibits the translation component elongation factor G. The response of P.
Russell A Johnson +2 more
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STUDY OF ANTIMICROBIAL ACTIVITY OF "FUZIPAN-DERMA" GEL [PDF]
Annals of Mechnikov's Institute, 2018 Introduction. Providing the population with effective drugs for the treatment of infectious diseases of the skin has an important medical and socio-economic significance.
Bayva P. P. +3 more
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Susceptibility in vitro of canine methicillin-resistant and -susceptible staphylococcal isolates to fusidic acid, chlorhexidine and miconazole: opportunities for topical therapy of canine superficial pyoderma [PDF]
, 2015 OBJECTIVES: Increasing multidrug resistance amongst canine pathogenic staphylococci has renewed interest in topical antibacterial therapy for skin infections in the context of responsible veterinary prescribing.
A. Loeffler +8 more
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Scientific Reports, 2021 While many data on molecular epidemiology of MRSA are available for North America, Western Europe and Australia, much less is known on the distribution of MRSA clones elsewhere.
S. Monecke +17 more
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Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid [PDF]
, 2017 BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice.
A Loeffler +29 more
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Journal of Antimicrobial Chemotherapy, 2021 BACKGROUND Current antimicrobial susceptibility/resistance data versus skin and soft tissue infection (SSTI) pathogens help to guide empirical treatment using topical antimicrobials.
G. Zhanel +4 more
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