Polymyxin B and fusidic acid, a novel potent synergistic combination against Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance [PDF]
Frontiers in Microbiology, 2023 The increasing prevalence of multidrug-resistant (MDR) Gram-negative bacteria and comparatively limited options of antibiotics pose a major threat to public health worldwide.
Shuying Chen +12 more
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Development and characterization of niosomal gel of fusidic acid: in-vitro and ex-vivo approaches [PDF]
Designed Monomers and Polymers, 2022 Niosomes are multilamellar vesicles that efficiently deliver active substance into skin systemic circulation or skin layers. They are used in topical drug delivery system to enhance the skin permeation of active substance. So, the prime objective of this
Muhammad Khurram Waqas +9 more
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The anti-staphylococcal fusidic acid as an efflux pump inhibitor combined with fluconazole against vaginal candidiasis in mouse model [PDF]
BMC MicrobiologyBackground Candida albicans is the most common fungus that causes vaginal candidiasis in immunocompetent women and catastrophic infections in immunocompromised patients.
Salwa E. Gomaa +12 more
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Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane [PDF]
Scientific Reports, 2023 The antibiotic fusidic acid (FA) is used to treat Staphylococcus aureus infections. It inhibits protein synthesis by binding to elongation factor G (EF-G) and preventing its release from the ribosome after translocation.
Adrián González-López +7 more
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Profiles of Non-aureus Staphylococci in Retail Pork and Slaughterhouse Carcasses: Prevalence, Antimicrobial Resistance, and Genetic Determinant of Fusidic Acid Resistance [PDF]
Food Science of Animal Resources, 2022 As commensal colonizers in livestock, there has been little attention on staphylococci, especially non-aureus staphylococci (NAS), contaminating meat production chain.
Yu Jin Yang +6 more
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Novel Fusidic Acid Cream Containing Metal Ions and Natural Products against Multidrug-Resistant Bacteria [PDF]
Pharmaceutics, 2022 Background: Drug design and development to overcome antimicrobial resistance continues to be an area of research due to the evolution of microbial resistance mechanisms and the necessity for new treatments.
Hani Naseef +8 more
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Antibacterial Activity of Fusidic Acid-Loaded Electrospun Polylactide Fiber Fleeces Against Periodontopathogenic Species [PDF]
PharmaceuticsBackground/Objectives: The effect of fusidic acid on oral bacteria, especially on Gram- negative periodontopathogenic species, has not yet been investigated.
Bernd W. Sigusch +6 more
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Exploration of the Fusidic Acid Structure Activity Space for Antibiotic Activity [PDF]
MoleculesFusidic acid is a translation inhibitor with activity against major Gram-positive bacterial pathogens such as S. aureus. However, its activity against Gram-negatives is poor based on an inability to access its cytoplasmic target in these organisms ...
Yoon-Suk Kang +9 more
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Evaluation of resistance to fusidic acid in Staphylococci isolates [PDF]
Journal of Microbiology and Infectious Diseases, 2011 Objectives: Staphylococci were most prominent factors that responsible for skin, soft tissue and foreign body infections.Gaining resistance to methicillin and various antibiotics in these microorganisms over the years increased morbidityand mortality ...
Özcan Deveci1, Dilek Kılıç2, Sedat Kaygusuz2, Nihal Duruyürek2, Ciğdem Karabıçak1, Canan Ağalar1, Alicem Tekin3
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