Results 121 to 130 of about 3,721,647 (391)

Complete remission of NUP98 fusion-positive acute myeloid leukemia with the covalent menin inhibitor BMF-219, icovamenib

Haematologica
Not available.
Hetty E. Carraway, Joy Nakitandwe, Alexandru Cacovean, Yan Ma, Brian Munneke, Ganesh Waghmare, Clarissa Mandap, Uzma Ahmed, Nicole Kowalczyk, Thomas Butler, Stephan W. Morris   +10 more
doaj   +1 more source

Radar HRRP Target Recognition Based on Deep One-Dimensional Residual-Inception Network

IEEE Access, 2019
A novel radar target recognition method based on the deep one-dimensional residual-inception network is proposed for a high-resolution range profile (HRRP).
Chen Guo, You He, Haipeng Wang, Tao Jian, Shun Sun   +4 more
doaj   +1 more source

Adapting to the Desert

, 2010
UNLV researchers explore how inhabitants of arid lands are able not only to survive but thrive in one of the most hostile, extraordinary landscapes on ...
staff writer, UNLV Fusion
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Recent diagnostic developments at the 100 kJ-level laser facility in China

Matter and Radiation at Extremes, 2020
A 100 kJ-level laser facility has been designed to study inertial confinement fusion physics in China. This facility incorporates various diagnostic techniques, including optical, x-ray imaging, x-ray spectrum, and fusion product diagnostics, as well as ...
Feng Wang, Shaoen Jiang, Yongkun Ding, Shenye Liu, Jiamin Yang, Sanwei Li, Tianxuan Huang, Zhurong Cao, Zhenghua Yang, Xin Hu, Wenyong Miao, Jiyan Zhang, Zhebin Wang, Guohong Yang, Rongqing Yi, Qi Tang, Longyu Kuang, Zhichao Li, Dong Yang, Yulong Li, Xiaoshi Peng, Kuan Ren, Baohan Zhang   +22 more
doaj   +1 more source

Shadow Lane Campus

, 2010
UNLV has developed a new campus that has emerged as a leading facility for health, biomedical, and biotechnological ...
staff writer, UNLV Fusion
core  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Energy measurement system of a large-aperture high power laser experiment platform

High Power Laser Science and Engineering, 2013
An energy measurement system in a Large-aperture high power laser experiment platform is introduced. The entire measurement system includes five calorimeters, which carry out the energy measurement of the fundamental ...
Yanwen Xia, Yue Liang, Sen Li, Junpu Zhao, Zhitao Peng, Hongguang Li, Hua Liu, Zhihong Sun, Kuixing Zheng, Xiaofeng Wei   +9 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source