Results 121 to 130 of about 3,816,755 (370)

Systematic study of breakup effects on complete fusion at energies above the Coulomb barrier

open access: yes, 2014
A large number of complete fusion excitation functions of reactions including the breakup channel were measured in recent decades, especially in the last few years.
Gomes, P. R. S.   +4 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Complete remission of NUP98 fusion-positive acute myeloid leukemia with the covalent menin inhibitor BMF-219, icovamenib

open access: yesHaematologica
Not available.
Hetty E. Carraway   +10 more
doaj   +1 more source

Radar HRRP Target Recognition Based on Deep One-Dimensional Residual-Inception Network

open access: yesIEEE Access, 2019
A novel radar target recognition method based on the deep one-dimensional residual-inception network is proposed for a high-resolution range profile (HRRP).
Chen Guo   +4 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Compare and contrast between duals of fusion and discrete frames

open access: yes, 2016
Fusion frames are valuable generalizations of discrete frames. Most concepts of fusion frames are shared by discrete frames. However, the dual setting is so complicated.
Arefijamaal, Ali Akbar, Osgooei, Elnaz
core   +1 more source

Polyetheretherketone as a Biomaterial for Spinal Applications [PDF]

open access: yes, 2006
Threaded lumbar interbody spinal fusion devices (TIBFD) made from titanium have been reported to be 90% effective for single-level lumbar interbody fusion, although radiographic determination of fusion has been intensely debated in the literature.
Estes, Bradley T.   +5 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Energy measurement system of a large-aperture high power laser experiment platform

open access: yesHigh Power Laser Science and Engineering, 2013
An energy measurement system in a Large-aperture high power laser experiment platform is introduced. The entire measurement system includes five calorimeters, which carry out the energy measurement of the fundamental ...
Yanwen Xia   +9 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

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