Results 121 to 130 of about 1,777,078 (318)

Inhibition of Akt activity and calcium channel function coordinately drive cell-cell fusion in the BeWO choriocarcinoma placental cell line [PDF]

open access: yes, 2012
To establish a simple and quantitative live cell fusion assay for placental syncytialization, we generated stable GFP and dsRed expressing fusogenic BeWo cell lines.
Bastie, Claire C.   +23 more
core   +1 more source

Radar Target Recognition Based on Feature Pyramid Fusion Lightweight CNN

open access: yesIEEE Access, 2019
In order to improve the accuracy and robustness of radar target recognition under low SNR conditions, a novel radar high range resolution profile (HRRP) target recognition method based on feature pyramid fusion lightweight CNN is proposed in this paper ...
Chen Guo   +4 more
doaj   +1 more source

Membrane fusion

open access: yesCurrent Opinion in Cell Biology, 2002
Fusion of biological membranes is governed by physical principles but it is unclear whether the transition states are primarily determined by lipid physics or by protein-lipid interactions. Recent advances in the field include the physical description of bilayer fusion, particularly new models beyond continuum models and the role of the SNARE proteins.
Jahn, R., Grubmueller, H.
openaire   +4 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Complete remission of NUP98 fusion-positive acute myeloid leukemia with the covalent menin inhibitor BMF-219, icovamenib

open access: yesHaematologica
Not available.
Hetty E. Carraway   +10 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Improving acoustic vehicle classification by information fusion

open access: yes, 2011
We present an information fusion approach for ground vehicle classification based on the emitted acoustic signal. Many acoustic factors can contribute to the classification accuracy of working ground vehicles.
Mark S. Nixon   +5 more
core   +1 more source

Radar HRRP Target Recognition Based on Deep One-Dimensional Residual-Inception Network

open access: yesIEEE Access, 2019
A novel radar target recognition method based on the deep one-dimensional residual-inception network is proposed for a high-resolution range profile (HRRP).
Chen Guo   +4 more
doaj   +1 more source

Fusion and “contra fusion”

open access: yesBabel. Revue internationale de la traduction / International Journal of Translation / Revista Internacional de Traducción
Abstract This article investigates Lawrence Venuti’s English translation of Edward Hopper , a Catalan poetry collection by Ernest Farrés inspired by the American painter’s work.
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy