Results 81 to 90 of about 1,982,523 (302)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Statistical image fusion with generalised Gaussian and Alpha-Stable distributions [PDF]
, 2007 This paper describes a new methodology for multimodal image fusion based on non-Gaussian statistical modelling of wavelet coefficients of the input images.
Loza, AT +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
At the Front of Fusion Research" -Introductory Lecture Open to Public- [PDF]
, 1993 An introductory lecture for the fusion research was held on October 21, 1992 at Nagoya University, on occasion of the 'Open School for Atomic Energy'. The school was organized by Atomic Energy Society of Japan.
ITOH, Kimitaka
core
Active Supercontinuum Injection for Optical Parametric Chirped Pulse Amplification
IEEE Photonics Journal, 2017 The anticipant supercontinuum is a prerequisite for the pump seed generation in an optical parametric chirped pulse amplification (OPCPA) system. To achieve the anticipant supercontinuum, we develop an active method operated in a two-level control scheme
Jie Mu +11 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Sea-detecting X-band Radar and Data Acquisition Program
Leida xuebao, 2019 To meet the radar data requirements of target detection technology research and address the lack of publicly available sea-detecting radar data, a data-sharing program for sea-detecting radar is proposed herein.
LIU Ningbo +7 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source