Results 131 to 140 of about 3,005 (266)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Editorial: Recent advances in mitochondria-associated endoplasmic reticulum membranes (MAMs) in heart-related diseases: volume II. [PDF]

Front Cardiovasc Med
Zhang Z, Ren K, Yang Y.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Case Report: Missed diagnosis of twin reversed arterial perfusion sequence discovered at delivery: lessons from poorly monitored monochorionic twin pregnancy. [PDF]

Front Med (Lausanne)
Houmaid H, Sali M, Harou K, Fakhir B, Boukhanni L, Asmouki H, Soummani A.   +6 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Future challenges for structural integrity of high-Iintegrity components. [PDF]

Philos Trans A Math Phys Eng Sci
Sharples JK, Ainsworth R.
europepmc   +1 more source

Blanket Technology for the Fusion Reactor

, 2016
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Helium-induced defect clustering and thermal evolution in V-4Cr-4Ti: an alloy for fusion reactor applications. [PDF]

Sci Rep
Ramachandran R, Nebula SU, David C, Balaji S, Suresh K.   +4 more
europepmc   +1 more source

Cylindrical breeding blankets for fusion reactors

Cylindrical breeding blankets for fusion reactors
Blankets with a cylindrical structure have been developed for a water-cooled ceramic breeder concept considering a pipe break inside the blanket container. Most existing studies have examined a box structure for the blanket container. Structural change from a box to a cylinder can decrease in first wall thickness while maintaining the pressure ...
openaire