Results 91 to 100 of about 501,769 (342)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Princeton Fusion Power Plant superconducting magnet system and costs [PDF]

, 1975
The Princeton University Reference Design of a proposed fusion power plant has been previously described. This paper describes details of the superconducting magnet system consisting of toroidal field, divertor, ohmic heating, equilibrium field and ...
File, J.
core  

Thermodynamic and economic analyses of the retrofit of existing electric power plants with fusion reactors

Energy Conversion and Management: X
Electricity generation will need to reach net zero emissions globally in 2050. This will require an increase in share of renewable energy and the implementation of a controllable carbon-free base-load source.
Francesca R. Famà, Victor Prost, Giuseppe Calabrò, Francesco A. Volpe, Stefano Ubertini, Andrea L. Facci   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The Selection of Power Cycle Technology for the Power Generation Island of a Thermonuclear Fusion Power Plant

南方能源建设
[Objective] By adding an energy storage loop, the intermittent energy produced by a thermonuclear fusion reactor can be converted into continuous energy.
Donglei WANG, Qi CHEN, Daqian XU, Xiao SUN, Xianyong LUO, Guangtao ZHU   +5 more
doaj   +1 more source

Stress, strain, neutron transport and radiation effects in a full fusion tokamak device: A virtual MAST-U study [PDF]

EPJ Web of Conferences
A finite-element method (FEM) model for the Mega-Ampere Spherical Tokamak - Upgrade (MAST-U) fusion tokamak has been developed to evaluate stress and deformations in the full device structure and to assess the stability of the whole tokamak with respect ...
Reali Luca, Ellis William M.E., Gray Ander, Boleininger Max, Davis Andrew, Brooks Helen M., Katramados Ioannis, Thornton Andrew J., Buchanan James, Dudarev Sergei L.   +9 more
doaj   +1 more source

Safeguard Requirements for Fusion Power Plants [PDF]

, 2012
Nuclear proliferation risks from magnetic fusion energy associated with access to fissile materials can be divided into three main categories: 1) clandestine production of fissile material in an undeclared facility, 2) covert production and diversion of such material in a declared and safeguarded facility, and 3) use of a declared facility in a ...
Glaser, Robert J. Goldston, Alexander
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source