Results 71 to 80 of about 8,177,292 (310)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Current fusion power plant design concepts

, 1976
Nine current U.S. designs for fusion power plants are described in this document. Summary tabulations include a tenth concept, for which the design document was unavailable during preparation of the descriptions.
Gore, B. F., Murphy, E. S.
core   +1 more source

Phase I: Natural Gas-Based Energy Storage at Abbott Power Plant [PDF]

, 2021
"University of Illinois will conduct a conceptual design study for integrating a 10 MWh Compressed Natural Gas Energy Storage (CNGES) system with the Abbott Combined Heat and Power Plant at the University of Illinois at Urbana-Champaign. CNGES technology
Attalla, Mohamed, OBrien, Kevin
core  

Hybrid hydrogen-electricity production using spherical tokamaks: a cost-driver sensitivity study and techno-economic analysis

Nuclear Fusion
Hybrid fusion power plants, which produce both hydrogen and electricity, are proposed as a way to decarbonise the fossil-fuel-dominated primary energy market and improve plant economics.
J. Hidalgo-Salaverri, T. Griffiths, Z. Xuereb Conti, P. Cano-Megias, R. Chacartegui, M. Bluck, J. Ayllon-Guerola, A. Mancini, M. Garcia-Munoz, E. Viezzer   +9 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Multi-criteria integrated assessment framework and GIS applied to fusion power plant site selection considering infrastructure-related data at a European scale

Energy Strategy Reviews
Electricity is essential to human quality of life and should be generated in a sustainable, low-carbon, and environmentally responsible way to meet global demand. Nuclear fusion offers a clean energy opportunity to meet future energy needs.
Larissa Breuning, Martín Oviedo Pascottini, Albrecht Herrmann, Frédérick Bordry, Thomas Hamacher   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Assessment on Tokamak Fusion Power Plant to Contribute to Global Climate Stabilization in the Framework of Paris Agreement [PDF]

A cost model for a tokamak fusion power plant (FPP) is improved to evaluate material cost and manufacture cost, separately. Then, the improved cost model is applied to a commercial tokamak FPP, and reduction of FPP construction cost is investigated ...
Special Design Team for Fusion DEMO, Joint, 日渡, 良爾, 797149, 797148, 797147, 797146, Goto, Takuya, Hiwatari, Ryoji, Joint Special Design Team, for Fusion DEMO   +8 more
core  

Production of power plant inertial confinement fusion targets [PDF]

, 1977
Power plant applications of inertial confinement fusion require production of targets at rates of 1 to 10 per second. Techniques for setting up ''factory'' operations to produce both cryogenic and non-cryogenic targets are presented.
C.D. Hendricks, Hendricks, C.D.
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source