Integration of a virus membrane protein intothe lipid bilayer of target cells as a prerequisite for immune cytolysis. Specific cytolysis after virosome- target cell fusion [PDF]
Brør Morein+3 more
openalex +1 more source
Use of single-chain antibody derivatives for targeted drug delivery [PDF]
Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery.
Ahmadzadeh, V.+5 more
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Retention of purified proteins in resealed human erythrocyte ghosts and transfer by fusion into cultured murine recipient cells [PDF]
Wolfgang Wille, Klaus Willecke
openalex +1 more source
SbcCD regulation and localization in Escherichia coli [PDF]
The SbcCD complex and its homologues play important roles in DNA repair and in the maintenance of genome stability. In Escherichia coli, the in vitro functions of SbcCD have been well characterized, but its exact cellular role remains elusive.
Borking, Amanda+7 more
core +2 more sources
System for Cleavable Fc Fusion Proteins Using Tobacco Etch Virus (TEV) Protease
We describe a novel Fc fusion protein system that can be cleaved by tobacco etch virus (TEV) protease. This system is desirable because it takes advantage of the high specificity of TEV protease and its activity at 4°C.
Jeffrey Haspel+3 more
doaj +1 more source
Failure to cleave measles virus fusion protein in lymphoid cells. A possible mechanism for viral persistence in lymphocytes [PDF]
Ryo Fujinami, MBA Oldstone
openalex +1 more source
Fusoselect: cell-cell fusion activity engineered by directed evolution of a retroviral glycoprotein [PDF]
Membrane fusion plays a key role in many biological processes including vesicle trafficking, synaptic transmission, fertilization or cell entry of enveloped viruses. As a common feature the fusion process is mediated by distinct membrane proteins.
Braun, Gundula+5 more
core
Membrane fusion activity of vesicular stomatitis virus glycoprotein G is induced by low pH but not by heat or denaturant [PDF]
The fusogenic envelope glycoprotein G of the rhabdovirus vesicular stomatitis virus (VSV) induces membrane fusion at acidic pH. At acidic pH the G protein undergoes a major structural reorganization leading to the fusogenic conformation.
Epand, Raquel F+4 more
core +1 more source