Results 291 to 300 of about 979,221 (350)

A general computational design strategy for stabilizing viral class I fusion proteins. [PDF]

Nat Commun
Gonzalez KJ, Huang J, Criado MF, Banerjee A, Tompkins SM, Mousa JJ, Strauch EM.   +6 more
europepmc   +1 more source

A general computational design strategy for stabilizing viral class I fusion proteins

, 2023
Gonzalez KJ, Huang J, Criado MF, Banerjee A, Tompkins S, Mousa JJ, Strauch E.   +6 more
europepmc   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

Intein Based Fusion Proteins: Great Tags for the Soluble Production and Convenient Purification of Recombinant Proteins. [PDF]

Iran J Biotechnol
Shafiee F, Sharifi S, Amini A.
europepmc   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins. [PDF]

Exp Hematol Oncol
Chen TQ, Huang HJ, Zhu SX, Chen XT, Pu KJ, Wang D, An Y, Lian JY, Sun YM, Chen YQ, Wang WT.   +10 more
europepmc   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman, Graham F. Barber, S'Dravious A. DeVeaux, Edward A. Botchwey, Daniel Refai, Adam M. Klein, Andrés J. García   +6 more
wiley   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Immunoprotection of FliBc chimeric fiber2 fusion proteins targeting dendritic cells against Fowl adenovirus serotype 4 infection. [PDF]

Poult Sci
Li Y, Zhou H, Li B, Li J, Shen Y, Jiang Y, Cui W, Tang L.   +7 more
europepmc   +1 more source