Results 141 to 150 of about 3,615,745 (273)

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 2, Page 492-501, March 2026.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki   +9 more
wiley   +1 more source

Intratumoral Fusobacterium nucleatum Drives Cancer‐Associated Fibroblasts Enrichment and Immune Exclusion in Esophageal Squamous Cell Carcinoma

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 2, Page 611-620, March 2026.
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi   +9 more
wiley   +1 more source

Fusobacterium in the microbiome: from health to disease across the oral-gut axis and beyond. [PDF]

open access: yesNPJ Biofilms Microbiomes
Li Z   +8 more
europepmc   +1 more source

Deep Tracking Neck Abscesses, Mediastinitis, and Deep Vein Thrombosis Caused by Aggregatibacter actinomycetemcomitans

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT This case report describes a novel presentation of Aggregatibacter actinomycetemcomitans causing deep neck abscess, mediastinitis, and deep vein thrombosis. Clinicians should be aware that this organism can cause invasive extra‐oral infection.
Joshua Sia, Carly Hughes
wiley   +1 more source

Polymicrobial Pasteurella multocida‐Anaerobic Coinfection Followhing a Cat Bite: Limb Salvage Through Metagenomic Next‐Generation Sequencing‐Guided Diagnosis and Multidisciplinary Management

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Successful management of a Pasteurella multocida and polymicrobial infection following a cat bite on the left leg entailed debridement, split‐thickness skin grafting with vacuum‐sealing drainage, and targeted antibiotic treatment. This approach enabled successful incorporation of the skin graft, preserving the limb and eliminating the ...
Yuanqing Qu   +4 more
wiley   +1 more source

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