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Increasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen [PDF]

open access: yesPLoS ONE, 2022
Infections caused by Fusobacterium species are rare; however serious infections with complications or mortality may occur occasionally. We conducted a retrospective study to investigate the clinical features of patients with Fusobacterium infections and ...
Jun Yong Choi, Su Jin Jeong
exaly   +8 more sources

Fusobacterium and Colorectal Cancer [PDF]

open access: yesFrontiers in Oncology, 2018
Colorectal cancer (CRC) is the third most common cancer worldwide and its pathogenesis has been extensively explored over the past decades. Recently, microorganisms in the gastrointestinal tract have emerged as potential etiological agents. In particular,
Jiewen Chen, Herui Yao, Hai Hu
exaly   +6 more sources

Full-length 16S rRNA nanopore sequencing enables species resolution of Fusobacterium associated with colorectal cancer [PDF]

open access: yesGut Microbes
Recent studies have revealed that the long-recognized link between the historically defined Fusobacterium nucleatum group and colorectal cancer is largely driven by Fusobacterium animalis.
William Rosenbaum   +6 more
doaj   +2 more sources

Enrichment of T: A→A: T substitutions in the TP53 gene in esophageal carcinoma with high Fusobacterium burden [PDF]

open access: yesScientific Reports
Exogenous lifestyle and environmental risk factors impact mutation burden in both benign and cancerous tissues. Moreover, interactions between the mucosa-associated microbiome and such genotoxic changes have been implicated in several cancer types.
Tomomitsu Tahara   +10 more
doaj   +2 more sources

Integrating ANI and phylogenies for re-evaluation of Fusobacterium taxonomy and disease associations [PDF]

open access: yesNature Communications
The genus Fusobacterium encompasses significant pathogens implicated in diseases spanning from infections to cancer. However, taxonomic ambiguities persist within the genus, particularly concerning Fusobacterium nucleatum (sensu lato). Through genus-wide
Dexi Bi   +10 more
doaj   +2 more sources

Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models

open access: yesMBio, 2022
Fusobacteria are commonly associated with human colorectal cancer (CRC), but investigations are hampered by the absence of a stably colonized murine model.
Barath Udayasuryan   +2 more
exaly   +3 more sources

Beyond a single species: Mapping virulence traits across the redefined Fusobacterium nucleatum complex [PDF]

open access: yesVirulence
Fusobacterium nucleatum was long regarded as a single species and later subdivided into four subspecies (nucleatum, polymorphum, animalis, vincentii/fusiforme).
Marietta Wolf   +7 more
doaj   +2 more sources

A Modified Method Incorporating Multiplex PCR Reveals Fusobacterium Prevalence in Southern Chinese Population and Its Correlations in Cancers [PDF]

open access: yesMicrobial Biotechnology
Fusobacterium, a gram‐negative anaerobic bacillus in mouth, gastrointestinal tract and elsewhere, has long been considered as opportunistic pathogen. Increasing evidence indicate the association of Fusobacterium with human diseases, especially cancer ...
Tingting Shen   +19 more
doaj   +2 more sources

Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance

open access: yesCancer Biology and Therapy
Fusobacterium nucleatum, an anaerobic Gram-negative bacterium primarily residing in the oral cavity, has garnered significant attention for its emerging role in cancer progression and prognosis.
Haitao Sun
exaly   +3 more sources

Oncobiome and personalized cancer medicine: myth or reality? [PDF]

open access: yesWorld Cancer Research Journal, 2021
The human body is a complex ecosystem inhabited and influenced by an abundance of microorganisms that include bacteria, viruses, fungi, archaea, and protozoa, which collectively make up the commensal microbiota.
M. Romeo
doaj   +1 more source

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