Results 1 to 10 of about 34,920 (110)

Full-length 16S rRNA nanopore sequencing enables species resolution of Fusobacterium associated with colorectal cancer [PDF]

Gut Microbes
Recent studies have revealed that the long-recognized link between the historically defined Fusobacterium nucleatum group and colorectal cancer is largely driven by Fusobacterium animalis.
William Rosenbaum, Marina Rubio Garcia, Anna Löfgren-Burström, Pär Larsson, Sofia Edin, Vicky Bronnec, Richard Palmqvist   +6 more
doaj   +2 more sources

Enrichment of T: A→A: T substitutions in the TP53 gene in esophageal carcinoma with high Fusobacterium burden [PDF]

Scientific Reports
Exogenous lifestyle and environmental risk factors impact mutation burden in both benign and cancerous tissues. Moreover, interactions between the mucosa-associated microbiome and such genotoxic changes have been implicated in several cancer types.
Tomomitsu Tahara, Takuya Shijimaya, Jumpei Yamazaki, Tsubasa Shimogama, Sanshiro Kobayashi, Naohiro Nakamura, Yu Takahashi, Takashi Tomiyama, Toshiro Fukui, Tomoyuki Shibata, Makoto Naganuma   +10 more
doaj   +2 more sources

Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF

Journal of Oral Microbiology, 2019
Neisseria meningitidis, Haemophilus influenzae, and Moraxella catarrhalis are pathogenic bacteria adapted to reside on human respiratory mucosal epithelia.
Bernhard B Singer, Leo Brady, Matt Brewer   +2 more
exaly   +2 more sources

Increasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen

PLoS ONE, 2022
Infections caused by Fusobacterium species are rare; however serious infections with complications or mortality may occur occasionally. We conducted a retrospective study to investigate the clinical features of patients with Fusobacterium infections and ...
Jun Yong Choi, Su Jin Jeong
exaly   +4 more sources

Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models

MBio, 2022
Fusobacteria are commonly associated with human colorectal cancer (CRC), but investigations are hampered by the absence of a stably colonized murine model.
Daniel Slade, Scott Verbridge, Shaoguang Wu   +2 more
exaly   +3 more sources

Integrating ANI and phylogenies for re-evaluation of Fusobacterium taxonomy and disease associations [PDF]

Nature Communications
The genus Fusobacterium encompasses significant pathogens implicated in diseases spanning from infections to cancer. However, taxonomic ambiguities persist within the genus, particularly concerning Fusobacterium nucleatum (sensu lato). Through genus-wide
Dexi Bi, Yuli Wu, Guo Ji, Xingchen Zhu, Hao Li, Ruting Xie, Yaohui Gao, Zixin Deng, Dongyan Han, Huanlong Qin, Qing Wei   +10 more
doaj   +2 more sources

Fusobacterium and Colorectal Cancer

Frontiers in Oncology, 2018
Colorectal cancer (CRC) is the third most common cancer worldwide and its pathogenesis has been extensively explored over the past decades. Recently, microorganisms in the gastrointestinal tract have emerged as potential etiological agents. In particular,
Herui Yao, Hai Hu, Jiewen Chen
exaly   +3 more sources

Reassessing taxonomy and virulence in the Fusobacterium nucleatum group—rebuttal of Fusobacterium animalis clades “ Fna C1” and “ Fna C2,” genome announcement for Fusobacterium watanabei, and description of Fusobacterium paranimalis sp. nov.

MBio
There is a considerable interest in the association between Fusobacterium animalis and colorectal cancer (CRC). Recently, it was suggested that this association is valid only for a distinct clade of F. animalis (Fna C2) and that F.
Diego Forni, Manuela Sironi, Öyvind Kommedal   +2 more
exaly   +3 more sources

A Modified Method Incorporating Multiplex PCR Reveals Fusobacterium Prevalence in Southern Chinese Population and Its Correlations in Cancers [PDF]

Microbial Biotechnology
Fusobacterium, a gram‐negative anaerobic bacillus in mouth, gastrointestinal tract and elsewhere, has long been considered as opportunistic pathogen. Increasing evidence indicate the association of Fusobacterium with human diseases, especially cancer ...
Tingting Shen, Jiarui Liang, Xuyu Li, Xiaoxie Xu, Liqiong Li, Yinjuan Xu, Shanshui Zeng, Bingyu Li, Hui Li, Mengyao Hu, Lang Zhou, Siqi Yan, Ya Zhang, Ziwei Zhou, Huaaishi Liang, Shulei Chen, Zhikun Liang, Congrong Wang, Hongwei Zhou, Dongxin Zhang   +19 more
doaj   +2 more sources

Oncobiome and personalized cancer medicine: myth or reality? [PDF]

World Cancer Research Journal, 2021
The human body is a complex ecosystem inhabited and influenced by an abundance of microorganisms that include bacteria, viruses, fungi, archaea, and protozoa, which collectively make up the commensal microbiota.
M. Romeo
doaj   +1 more source