Results 111 to 120 of about 19,818,011 (289)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2009 Advocates of Open Access call to substitute the established scholarly publication model, in particular subscriptions and licences, by an Open Access Publishing model.
Bauer, Bruno, Reckling, Falk
doaj
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUAThe Architecture Biennale is entrusted with the mission of being a sensor of the future through a collection of possible actions in the present on a global scale.
Angela Palumbo
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The interaction between humans and knowledge management systems : rethinking the future [PDF]
, 2019 In this workshop position paper, we propose a study to understand the importance of knowledge management systems among academics in Saudi higher education institutions, admitting that knowledge workers and Knowledge Management Systems are valuable ...
Almujally, Nouf, Joy, Mike
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
AN EVOLVING VISION OF GOD: THE THEOLOGY OF JOHN F. HAUGHT
Zygon, 2010 The theology of God in the scholarship of John Haught exemplifies rigor, resourcefulness, and creativity in response to ever‐evolving worldviews. Haught presents insightful and plausible ways in which to speak about the mystery of God in a variety of ...
doaj +2 more sources
Future craft:research exposition [PDF]
, 2010 Past, Present and Future Craft Practice has sought to use the Future Craft exposition as a vehicle for showcasing its research. The exposition was chosen over the exhibition as it opens up a dialogue with the audience on the work undertaken.
Follett, Georgina, Valentine, Louise
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