Results 111 to 120 of about 4,960,795 (251)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

German Future Earth Summit (2014) Conference Summary Report 27. / 28. Jan 2014 Berlin [PDF]

open access: yes, 2014
Als Teil des nationalen Themenfindungsprozesses setzte sich das erste German Future Earth Summit zum Ziel, die deutsche akademische Community zu stärken und in einem interdisziplinären Umfeld innovative Themenschwerpunkte zu diskutieren.

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

AN EVOLVING VISION OF GOD: THE THEOLOGY OF JOHN F. HAUGHT

open access: yesZygon, 2010
The theology of God in the scholarship of John Haught exemplifies rigor, resourcefulness, and creativity in response to ever‐evolving worldviews. Haught presents insightful and plausible ways in which to speak about the mystery of God in a variety of ...
doaj   +2 more sources

Transforming the Future [PDF]

open access: yes, 2018
People are using the future to search for better ways to achieve sustainability, inclusiveness, prosperity, well-being and peace. In addition, the way the future is understood and used is changing in almost all domains, from social science to daily life.

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Les espaces oubliés des métropoles dans les imaginaires de la décarbonation

open access: yesArticulo: Journal of Urban Research
The article examines the representations of decarbonized metropolitan futures, highlighting the absence of representation for many metropolitan spaces identified as undesirable.
Louise Jammet
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Future Journal of Pharmaceutical Sciences

open access: yes, 2015
Future Journal of Pharmaceutical Sciences issued under the auspicious of Future University in Egypt. The Journal publishes communications, original research articles, review articles and case studies on all aspects of the pharmaceutical ...

core   +1 more source

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