Results 191 to 200 of about 20,478,757 (338)
Chronotype and academic procrastination: the chain mediating role of future self-continuity and self-control. [PDF]
BMC PsycholSong J, Lei Y, Zhang Y, Hu X.
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Writing the Past, Present, and Future: The Impact of Positive Psychology Expressive Writing on Adolescents' Time Attitudes. [PDF]
Behav Sci (Basel)Tu X, Wu B, Ding X, Huo Q, Chen M.
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Widespread heat stress will become the norm in a warming Southeast Asia. [PDF]
Sci RepManimaran S +6 more
europepmc +1 more source
Findings and recommendations for use by other citizens, local, state and federal policymakers, educators, and the food industry [PDF]
, 2002 Citizen Panel on the Future of Food in New England
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source