Results 61 to 70 of about 6,017,205 (215)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
TapuyaDuring the COVID-19 pandemic, Brazil was the target of great international concern due to the policies adopted by the far-right government of President Jair Bolsonaro.
Rosana Castro
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Visions profanes du futur de la mobilité spatiale
Temporalités, 2019 For the founding fathers of the social sciences, the future was key. Marx, Tarde, Durkheim, Weber address the question of Progress and long-term change in society.
Alexandre Rigal
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
“REDISCOVERY” OF KNOWLEDGE ABOUT THE FUTURE: PERSPECTIVES OF RUSSIA’S SECURITY UP TO 2050
Vestnik MGIMO-Universiteta, 2017 The article deals with the dynamics of knowledge about the future, factors that determine the need for its »rediscovery« today, among which: the transition of mankind to the dominance of non-linear development; the destruction by globalization of the ...
S. A. Kravchenko, A. I. Podberezkin
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Developing A Perception Scale For The Future of Nursing
Sağlık ve Hemşirelik Yönetimi DergisiAim: The aim of the research is to develop the Perception Scale for the Future of Nursing to be used to determine the perception of the future of nursing.
Saadet Meriç, Sevim Ulupınar
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