Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Augmenting the Future Liver Remnant Prior to Major Hepatectomy: A Review of Options on the Menu. [PDF]
Wong P +5 more
europepmc +1 more source
Functional transition: Inconsistently parallel to the increase in future liver remnant volume after preoperative portal vein embolization. [PDF]
Tsuruga Y +9 more
europepmc +1 more source
Exploring Radiomics as a Predictor of hypertrophy of Future Liver Remnant after Portal Vein Embolization in Biliary Malignancies: A Retrospective Cohort Study [PDF]
Piyush Aggarwal +2 more
openalex +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy. [PDF]
Korenblik R +120 more
europepmc +1 more source
ASO Visual Abstract: Augmenting the Future Liver Remnant Prior to Major Hepatectomy: A Review of Options on the Menu [PDF]
Paul Wong, Laleh G. Melstrom
openalex +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Induction of Robust Future Liver Remnant Hypertrophy Before Hepatectomy With a Modified Liver Venous Deprivation Technique Using a Trans-venous Access for Hepatic Vein Embolization. [PDF]
Degrauwe N +5 more
europepmc +1 more source
Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT [PDF]
Bård I. Røsok +8 more
openalex +1 more source

