Results 71 to 80 of about 787,698 (305)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

New perspectives on computer concepts, 2010, comprehensive / Parsons, Oja.

, 2010
Accompanying BookOnCD contains the entire contents of the textbook with figures that come to life as videos, software tours, and animations. Includes also labs and computer-scored practice tests.Includes indexxxiii, 749 pages. :Get Synched!
Parsons, June Jamrich., 422 author., Oja, Dan, 434 author.   +1 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Future Perspectives on Black Hole Jet Mechanisms: Insights from Next-Generation Observatories and Theoretical Developments

Universe
Black hole jets represent one of the most extreme manifestations of astrophysical processes, linking accretion physics, relativistic magnetohydrodynamics, and large-scale feedback in galaxies and clusters. Despite decades of observational and theoretical
Andre L. B. Ribeiro, Nathalia M. N. da Rocha   +1 more
doaj   +1 more source

Land Use Carbon Emissions or Sink: Research Characteristics, Hotspots and Future Perspectives [PDF]

The land use, land-use change and forestry (LULUCF) sector, as a source and a sink of greenhouse gas (GHG) emissions, is critical for achieving carbon neutrality.
Shaojian Wang, Maraseni, Tek Narayan, Lina Liu, Rong Wu, Wang, Shaojian, Jiansheng Qu, Suman Aryal, Zhang, Zhenhua, Wu, Rong, Qu, Jiansheng, Feng Gao, Aryal, Suman, Gao, Feng, Liu, Lina, Zhenhua Zhang, Tek Narayan Maraseni   +15 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From Machine Learning to Patient Outcomes: A Comprehensive Review of AI in Pancreatic Cancer

Diagnostics
Pancreatic cancer is a highly aggressive and difficult-to-detect cancer with a poor prognosis. Late diagnosis is common due to a lack of early symptoms, specific markers, and the challenging location of the pancreas.
Satvik Tripathi, Azadeh Tabari, Arian Mansur, Harika Dabbara, Christopher P. Bridge, Dania Daye   +5 more
doaj   +1 more source

Application of FMEA in the automotive industry: Present situation and perspectives in the Republic of Serbia [PDF]

Trendovi u Poslovanju
This paper conducts an analysis of the application of FMEA in companies operating in the automotive industry within the territory of the Republic of Serbia, focusing on the current situation and future perspectives.
Tadić Danijela, Banduka Nikola, Petrović Tijana, Komatina Nikola   +3 more
doaj   +1 more source

Original article Future perspectives as a condition of positive adaptation of young adults after traumatic experience

, 2014
Background The paper presents the results of a study on the possible role of sense of influencing one’s life and expectations towards the future as a personal condition of adaptation.
Marzanna Farnicka
core   +1 more source