Results 121 to 130 of about 86,286 (264)

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

FORMATION OF UNIVERSAL COMPETENCE IN FUTURE PRIMARY SCHOOL TEACHERS

This article studies the theoretical foundations and practical directions of the formation of universal competence in future primary school teachers. Literature analysis, survey and pedagogical observation were used as research methods. The results show that special curricula, intercultural dialogue trainings and practices are important for the ...
openaire   +2 more sources

Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics

Advanced Science, EarlyView.
Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai, Ri He, Junxian Liu, Liangzhi Kou   +3 more
wiley   +1 more source

DEVELOPING ECONOMIC LITERACY IN FUTURE PRIMARY SCHOOL TEACHERS

The formation of economic literacy in primary school students is a critical task in modern education. Future primary school teachers must be equipped with effective methods and tools to instill basic financial and economic concepts in young learners.
openaire   +2 more sources

Development of ICT competence of the future primary school teacher

Scientific Herald of Uzhhorod University Series Physics
Relevance. The relevance of the study is conditioned by the problem of expanding the educational space by introducing high capabilities of information and communication technologies that allow improving educational activities in primary school. Purpose.
Kaldykul Sarbassova, Nurzhamal Oshanova, Maral Tolykbayeva, Aray Satybaldy, Ulzhan Abdikadyrova   +4 more
openaire   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

Advanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

PROVIDING EDUCATIONAL ENVIRONMENT FOR PRIMARY SCHOOL PUPILS: PERSONAL AND PROFESSIONAL VOCATION OF A MODERN SCHOOL TEACHER

Наукові записки Тернопільського національного педагогічного університету імені Володимира Гнатюка. Серія: Педагогіка, 2016
The article modifies the necessity to deepen the scientific understanding of the process of forming the ability of future primary school teachers to design the teaching educational environment of modern primary school which is the resource of ...
Nadiya Kichuk
doaj  

Why Didn't I Get a Payout? Understanding Farmer Choices, Index Insurance, and Basis Risk

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Index insurance, while heralded as a potential solution to alleviate poverty and food insecurity among agricultural households, has its own set of challenges, notably basis risk. Basis risk is the discrepancy between the insurance payout and losses incurred, posing a significant deterrent to the adoption of index insurance.
S. Lucille Blakeley, Sean Posey, Kathy Baylis, Daniel Osgood, Stuart Sweeney   +4 more
wiley   +1 more source