CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction
Advanced Science, EarlyView.CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su +5 more
wiley +1 more source
How transformational leadership is associated with primary and secondary school teachers' social-emotional competence: a multiple mediation analysis. [PDF]
Front PsycholLi Q, Tu J, Zeng B.
europepmc +1 more source
IMPROVING THE PROFESSIONAL COMPETENCE OF FUTURE PRIMARY SCHOOL TEACHERS
The main content of this article is enriched with theoretical and scientific-practical insights into improving the professional competence of primary school teachers through the use of learner-centered education, as well as reflections on the objectives and expected outcomes of applying this approach.
openaire +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Balancing beliefs: exploring preservice teachers' generative artificial intelligence perceptions and intentions for practice. [PDF]
Front Artif IntellKarlin M +3 more
europepmc +1 more source
From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology
Advanced Science, EarlyView.Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño +9 more
wiley +1 more source
Leisure time satisfaction as a predictor of life satisfaction among teachers. [PDF]
Front PsycholKaradayi F, İyikal Çelebi A, Şenol H.
europepmc +1 more source
Robust Stitching Interface and Deep Learning Empowered Hydrogel Human‐Machine Interface
Advanced Science, EarlyView.A molecular design strategy is presented that exploits synergistic carboxylate anion–quaternary ammonium interactions to simultaneously strengthen the hydrogel–PET interface and the bulk hydrogel network. Integrated with deep learning signal processing, the stable hydrogel–PET interface enables consistent signal acquisition and reliable human‐machine ...
Hao Dong +11 more
wiley +1 more source
Teaching beliefs and wellbeing among primary school teachers: a moderated mediation of work engagement and career adaptability. [PDF]
Front PsycholWang J, Xu X.
europepmc +1 more source
Why Didn't I Get a Payout? Understanding Farmer Choices, Index Insurance, and Basis Risk
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Index insurance, while heralded as a potential solution to alleviate poverty and food insecurity among agricultural households, has its own set of challenges, notably basis risk. Basis risk is the discrepancy between the insurance payout and losses incurred, posing a significant deterrent to the adoption of index insurance.
S. Lucille Blakeley +4 more
wiley +1 more source