Results 121 to 130 of about 7,990,158 (258)

Future Trends in Computing Technology in Education

, 2016
Future Trends in Computing Technology in ...
Uzunboylu, Huseyin, Garcia Laborda, Jesus, Uzunboylu,Huseyin, Ross, Steven, Garcia Laborda,Jesus, Ross,Steven   +5 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Change Trend and Prediction of Water Surface Evaporation in Shule River Basin from 1980 to 2020

Shuitu baochi yanjiu
[Objective]The aims of this study are to reveal the variation characteristics and future evolution trend of water surface evaporation in the Shule River Basin, to better understand the dynamic changes of water resources in the basin, so as to provide ...
Zhou Min, Sun Dongyuan, Zhao Yufeng, Hui Lei, Niu Zuirong, Ma Yali, Wu Lanzhen, Wang Xingfan   +7 more
doaj  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Coastal Reclamation Embankment Deformation: Dynamic Monitoring and Future Trend Prediction Using Multi-Temporal InSAR Technology in Funing Bay, China

Remote Sensing
Reclamation is an effective strategy for alleviating land scarcity in coastal areas, thereby providing additional arable land and opportunities for marine ranching.
Jinhua Huang, Baohang Wang, Xiaohe Cai, Bojie Yan, Guangrong Li, Wenhong Li, Chaoying Zhao, Liye Yang, Shouzhu Zheng, Linjie Cui   +9 more
doaj   +1 more source

The experience of the M.IT [PDF]

, 2011
Paper presented at the 2 day Seminar, 8-9 June 2011 "The e-Learning environment: future trends and impact on library services", Sanlam Auditorium, Conference Centre, Hatfield Campus, Pretoria, South Africa.SWETStheo.bothma@up.ac ...

core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Evolutionary characteristics, influencing factors of livestock and poultry meat production in China and its future trends

Animal Research and One Health
An accurate grasp of the current situation and the development trend of livestock and poultry meat production in China is helpful to better ensure the adequate and stable supply of the meat market.
Pengcheng Li, Robert Hoste, Zengyong Zhu, Kai Zhao, Chang Liu, Xinyi Yang, Xiwei Xu   +6 more
doaj   +1 more source

Review of design thermal loading for steel bridges in Hong Kong

, 2002
The 2nd International Conference on Current and Future Trends in Bridge Design, Hong Kong, 25-26 April 2001. In Current and Future Trends in Bridge Design, Construction and Maintenance, 2002, v. 2, p.
Au, FTK, Tong, M, Tham, LG
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