Results 71 to 80 of about 8,954,451 (298)

The 21st Century Singularity and its Big History Implications: A re-analysis

Journal of Big History, 2018
The idea that in the near future we should expect “the Singularity” has become quite popular recently, primarily thanks to the activities of Google technical director in the field of machine training Raymond Kurzweil and his book The Singularity Is Near (
Andrey Korotayev
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Wireless Fast Charging Solutions for Electric Vehicles: Future Trends and Technological Challenges [PDF]

E3S Web of Conferences
The rising adoption of electric vehicles (EVs) has exacerbated the need for efficient, user-friendly charging options. Wireless rapid charging presents a viable alternative to standard plug-in systems, with the possibility for greater convenience and ...
Mokshayini V., Sindhuri P., Vivek K., Mohanarao P.A., Swathi Aakula, Manoj Vasupalli   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Gauteng Community libraries information literacy [PDF]

, 2011
Paper presented at the 2 day Seminar, 8-9 June 2011 "The e-Learning environment: future trends and impact on library services", Sanlam Auditorium, Conference Centre, Hatfield Campus, Pretoria, South Africa ...
Meyer, Koekie
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Autonomous vehicles: state of art, future trends, and challenges

, 2019
Autonomous vehicles are considered to be the next big thing. Several companies are racing to put self-driving vehicles on the road by 2020. Regulations and standards are not ready for such a change.
Pelliccione, Patrizio, Patrizio Pelliccione, Nassar Mohammadiha, Mallozzi, Piergiuseppe, Alessia Knauss, Berger, Christian,, Piergiuseppe Mallozzi, Pelliccione, Patrizio,, Knauss, Alessia,, Mohammadiha, Nasser,, Knauss, Alessia, Berger, Christian, Christian Berger, Mohammadiha, Nasser, Mallozzi, Piergiuseppe,   +14 more
core   +1 more source

Characteristics， future trends and countermeasures of Chinese import and export market for bulk feed raw materials

Siliao yanjiu, 2023
The import and export trade of bulk feed raw materials is key point to ensure normal operation of animal husbandry, which is of great significance to sustainable development of animal husbandry.
LONG Xia, WANG Su-juan
doaj  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Global burden of disease changes related to high red meat diets and breast cancer from 1990 to 2021 and its prediction up to 2030

Frontiers in Nutrition
BackgroundBreast cancer associated with high red meat consumption has become a significant global health issue. This study aims to analyze the global and regional disease burden related to breast cancer attributable to high red meat diets from 1990 to ...
Yujun Tong, Hong Ning, Zhen Zhang, Xiaohong Zhang, HongMei Tu, Min Yang, Xiaoan Li, Tiantian Liang   +7 more
doaj   +1 more source