Results 61 to 70 of about 954,567 (310)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Integrating UAVs into Highway Infrastructure Management Across the Life Cycle: A Systematic Review and Research Outlook

open access: yesVehicles
Unmanned aerial vehicle (UAV) technology is becoming increasingly integrated into the full lifecycle management of expressways, emerging as a vital tool in the intelligent transformation of transportation infrastructure.
Yangyang Luo   +3 more
doaj   +1 more source

THE FUTURE OF CITIES: THE ROLE OF STRATEGIC PLANNING

open access: yes, 2013
Long term strategic plans are enjoying a renaissance in cities across the world. The strategic plans of London, Paris, Auckland, Johannesburg, Sao Paulo, Singapore, New York, and Barcelona are all examples of different ways that cities try to plot their ...
Clark, Greg
core   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Tracking the trends: future directions for human services in Edmonton. Special feature on families with children.

open access: yes, 1990
This second edition includes a focus on the social trends and service implications for families with ...
Community Trends Working Group
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Beyond the Trends: Evolution and Future Directions in Music Recommender Systems Research

open access: yesIEEE Access
The study of Music Recommender Systems (MRS) has become crucial in digital music consumption, influencing how people discover and interact with music.
Babak Amiri   +3 more
doaj   +1 more source

The 21st Century Singularity and its Big History Implications: A re-analysis

open access: yesJournal of Big History, 2018
The idea that in the near future we should expect “the Singularity” has become quite popular recently, primarily thanks to the activities of Google technical director in the field of machine training Raymond Kurzweil and his book The Singularity Is Near (
Andrey Korotayev
doaj   +1 more source

Future Trends and Challenges of Financial Risk Management in the Digital Economy

open access: yes, 2003
In this paper, the future trends and challenges of financial risk management are considered. First, the historical developments and current status of financial risk management are assessed.
Li, S., Li, Steven
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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