Results 241 to 250 of about 33,696,977 (337)

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Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Ethical frameworks and community engagement in HIV cure-related research at the end of life: looking back, moving forward. [PDF]

Curr Opin HIV AIDS
Ahmed A, Tran W, Ndukwe S, Sloane Z, Costiniuk C, Dubé K.   +5 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Habitat suitability and active component responses of <i>Eleutherococcus senticosus</i> under climate change: implications for conservation and wild tending. [PDF]

Front Plant Sci
Duan D, Xu H, You M, Li M, Chen J, Zhang B, Chen B, Jin X, Zhang X.   +8 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

The real option value of multistage agricultural research for development. [PDF]

PLoS One
Schiek B.
europepmc   +1 more source

Exploring Patient-Reported Outcome Measures and Patient-Reported Experience Measures in Cardiovascular Value-Based Healthcare. [PDF]

Nurs Health Sci
Soo Hoo SY, Kynoch K.
europepmc   +1 more source

Values for the future

Konttinen Annika, Seppänen Anu
openaire   +1 more source