Results 151 to 160 of about 45,810 (264)

Correction to: Co-design of the 'OurFutures Vaping' programme: a school-based eHealth intervention to prevent e-cigarette use. [PDF]

Health Promot Int
europepmc   +1 more source

The Futures of Digital Democracy: Four Scenarios. [PDF]

Open Res Eur
Fuchs C, Museba J, Friesch K.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Heat-related challenges and interventions in hospitals: A future-oriented, qualitative approach to improve nurses' working conditions. [PDF]

J Clim Chang Health
Zink M, Nakoinz A, Krol U, Jansen N, Jung F, Riedel-Heller SG, Gabriel KMA.   +6 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Climate-Driven Habitat Suitability Modeling for the Vulnerable Species <i>Euryops pinifolius</i> A. Rich in Ethiopia: Implications for Conservation. [PDF]

Ecol Evol
Birhanu L, Balzter H, Basell L, Burns M, Arega W, Gebeyehu Y.   +5 more
europepmc   +1 more source

Future of the Future

Futurity designing. Digital reality problems, 2018
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Sustainable regional corn yield prediction for the United States through interpretable machine learning approach. [PDF]

Sci Rep
Kehkashan T, Abdelhaq M, Al-Shamayleh AS, Hamza M, Khan MA, Alharthi SZ, Akhunzada A.   +6 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source