Results 81 to 90 of about 45,356 (264)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Los futuros de México: encrucijada y clavos en el zapato Mexico's futures: crossroad and pain in the neck

open access: yesPolis, 2011
El artículo propone que México tiene pendiente la tarea de imaginar sus futuros de largo plazo, planteando que es urgente que lo haga en un esfuerzo colectivo, sistemático y riguroso.
Antonio Alonso Concheiro
doaj  

Governing antimicrobial resistance in Norwegian livestock farming to 2050: a participatory strategy development approach

open access: yesFrontiers in Veterinary Science
Antimicrobial resistance (AMR) is a wicked problem with long-term and unpredictable impacts on human and animal health. Understanding how to govern AMR long-term, amidst evolving social, political, economic, technological and environmental changes which ...
Richard Helliwell   +4 more
doaj   +1 more source

Assessing Volatility Behaviors of Cross-Currency Derivatives in India's Exchange Markets Using Machine Learning Algorithms [PDF]

open access: yesAnnals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics
Currency Derivatives are very important financial instruments for speculation, hedging and arbitrage opportunities, and among them cross-country futures are one of the important types with a huge research gap. Studying them becomes very imperative.
Aman Shreevastava   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Engaging children's voices for tourism and marine futures through drawing in Gili Trawangan, Indonesia

open access: yesFrontiers in Sustainable Tourism
Ocean tourism is a primary source of income for many small-island and coastal communities. Participatory processes have been advocated to develop and implement community-based management plans to address various problems induced from tourism development ...
Yim Ming Connie Kwong
doaj   +1 more source

The issue of trust in knowledge about the future: with ref. to the 3rd Forum of the International sociological Association (Austria, Vienna, July 10-14, 2016)

open access: yesСоциологическая наука и социальная практика, 2016
A comparative analysis of the ideas about the future, being a subject of classical and modern sociology, is given, as well as new theoretical and methodological approaches to explore alternative options of the future which were presented at the 3rd Forum
Sergey A. Kravchenko
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

“Emotion is Another Kind of Information”

open access: yesArt/Research International
This review explores entanglements of the theoretical and affective impacts of an art exhibition called Caring Futures which was part of an interdisciplinary research project.
Ingvil Hellstrand   +4 more
doaj   +1 more source

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