Results 91 to 100 of about 9,288,027 (305)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Holograms or Hemorrhoids? Student Teachers’ Imaginings of the Digital Futures of Education

open access: yesNordic Studies in Education
This study reports preservice teachers’ perceptions of desirable and undesirable digital futures for education. Empathy-based stories were collected from 74 student teachers in Finnish professional teacher education.
Hanna Teräs   +2 more
doaj   +1 more source

Futures-focused leadership in New Zealand secondary schools [PDF]

open access: yes, 2009
This study explores the issues facing twenty-first century secondary school principals as they face changes in education brought about by the New Zealand Curriculum, and changes in their communities in the face of the emerging knowledge society.
Hayes, Juliette
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Families, Communities and Action Competence in Environmental and Sustainability Education: Reframing Learning for Sustainable Futures

open access: yesAustralian Journal of Environmental Education
The special issue, “Meeting Global Challenges through Families and Community Environmental and Sustainability Education: Generating Action Competence” aims to discover and address ways of meeting global educational and political challenges of sustainable
Laid Bouakaz, Dennis Beach
doaj   +1 more source

Let education theory go feral : four futures for education's non/human others

open access: yes, 2012
In Futures Studies, there is never only one single future to be addressed and explored, but several. These different futures can, to varying degrees and to various stakeholders, be possible, probable, and/or desirable.
Pedersen, Helena
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

The Future of Virology Education

open access: yesAnnual Review of Virology
The rapidly evolving pace of scientific information, technology, and innovation in pedagogical approaches provides an opportunity to consider the future of virology education. Virology curriculum guidelines for undergraduate and graduate education call for student-centered approaches with a focus on integrating concepts by virology topics rather than ...
openaire   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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