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Two New Alkaloids from Fuzi and Their Metabolites Study

Chemistry & Biodiversity, 2021
AbstractFormer study suggests alkaloids from herbs of Aconitum genus plants possess excellent bioactivities, which exert great value for related deeper chemical constituent investigation. Herein, chemical isolation was performed and four alkaloids were isolated from Fuzi, of which two were new ones, and the other two were reported NMR data for the ...
Sisi, Liu   +8 more
openaire   +2 more sources

A systematic review of pharmacokinetic studies on herbal drug Fuzi : Implications for Fuzi as personalized medicine

Phytomedicine, 2018
Fuzi, which is the processed lateral roots of Aconitum carmichaeli Debx. (Ranunculaceae), is a traditional herbal medicine that is well known for its excellent pharmacological effects and acute toxicity. Aconitum alkaloids are responsible for its pharmacological activity and toxicity.
Jin-Jun, Wu   +12 more
openaire   +2 more sources

Identification and comparative analysis of the major chemical constituents in the extracts of single Fuzi herb and Fuzi-Gancao herb-pair by UFLC-IT-TOF/MS

Chinese Journal of Natural Medicines, 2014
The aim of this work was to establish a specific and sensitive method to comprehensively investigate and compare chemical constituents of Fuzi-Gancao herb pair (FG), consisting of Aconitum carmichaelii Debeaux (Fuzi, Chinese) and Roast Radix Glycyrrhizae (Glycyrrhiza glabra L., Gancao, in Chinese) and Fuzi alone to explore the underlying interaction ...
Yan, Yang   +6 more
openaire   +2 more sources

[Compatability chemistry of acid-alkaline pair medicine of dahuang and Fuzi in Dahuang Fuzi decoction].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009
To determine the change pattern of alkaline and acid components of Dahuang and Fuzi in different combinations.The contents of anthraquinones and aconite alkaloids were determined by HPLC in samples of Dahuang extracts, Fuzi extracts, Dahuang and Fuzi pair medicines extracts, and extracts of whole recipe.As for Dahuang, the contents of anthraquinones ...
Xiujun, Duan   +2 more
openaire   +1 more source

Human PXR-mediated transcriptional activation of CYP3A4 by ‘Fuzi’ extracts

Toxicology Mechanisms and Methods, 2019
This study focused on determining whether the 'Fuzi' (FZ) extracts from different extraction methods are related to pregnane X receptor (PXR) and cytochrome P450 3A4 (CYP3A4), and explore the mechanism.FZ was extracted under various conditions, and the components were identified by Ultra Performance Liquid Chromatography/Quad Time of Flight Mass ...
Guangyao Huang   +9 more
openaire   +2 more sources

Pharmacokinetics of aconitine as the targeted marker of Fuzi (Aconitum carmichaeli) following single and multiple oral administrations of Fuzi extracts in rat by UPLC/MS/MS

Journal of Ethnopharmacology, 2012
Fuzi, which is the processed lateral roots of Aconitum Carmichaeli. Debx and is widely distributed over the southwest provinces of China, is recognised for its anti-inflammatory and analgesic effects.The pharmacokinetic properties of Fuzi are inadequately understood.
Lan, Tang   +5 more
openaire   +2 more sources

[Herbalogical study of Aconiti Lateralis Radix Praeparata(Fuzi)].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
As a most important Chinese materia medica, Aconiti Lateralis Radix Praeparata(Fuzi) had been widely used in China for thousands of years. This herbalogical study was systematically performed based on variation characteristics of the naming, habitat, harvesting, processing and properties.
Dong, Si-Han   +5 more
openaire   +2 more sources

Enhancement of Degraded Images via Fuzy Intensification Model

2021
The poor conditions of weather dust substantially reduce the overall quality of both the images taken, thus preventing useful image data from is being detected. A simple membership function is used in the proposed technique to set the pixels of a given channel to the range of zero to one, fluctuating intensifying operators applied according to various ...
Shaik Fayaz Begum, P. Swathi
openaire   +1 more source

Isolation and structural characterization of an immunostimulating polysaccharide from fuzi, Aconitum carmichaeli

Carbohydrate Research, 2006
A water-soluble polysaccharide named as FPS-1 was isolated from fuzi, the root of Aconitum carmichaeli Debx. by hot-water extraction, anion-exchange and gel-permeation chromatography and tested for its pharmacological activities. Its structural characteristics were investigated by FTIR, HPLC, NMR spectroscopy, methylation analysis and GLC-MS.
Chi, Zhao   +3 more
exaly   +3 more sources

Fuzi-Lizhong pill compensates hypothyroid-hypothermia via ghrelin release

Journal of Ethnopharmacology, 2013
Fuzi-Lizhong pill (FLZ) is a traditional Chinese medicine for treating patients with Spleen Yang deficient syndrome. Ghrelin, a peptide with 28 amino acid residues, plays multiple roles in thermogenesis. This study aims to explore FLZ regulating ghrelin to compensate hypothermia in rats with hypothyroid and indigestion.In litter-matched rats ...
Xin, Zhao   +8 more
openaire   +2 more sources

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