Results 51 to 60 of about 585 (260)

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

open access: yesAdvanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

On the Challenges and Opportunities of Fuzzing via Large Language Models: A Review

open access: yesApplied Sciences
Fuzzing is an important automated testing technique for discovering vulnerabilities and abnormal software behavior, but conventional and pre-LLM learning-based approaches often struggle with strict validity constraints, limited semantic understanding ...
Yiqing Sun   +3 more
doaj   +1 more source

FuzzE, Development of a Fuzzing Approach for Odoo's Tours Integration Testing Plateform

open access: yes2025 IEEE Conference on Software Testing, Verification and Validation (ICST)
For many years, Odoo, an open-source add-on-based platform offering an extensive range of functionalities, including Enterprise Resource Planning, has constantly expanded its scope, resulting in an increased complexity of its software. To cope with this evolution, Odoo has developed an integration testing system called tour execution, which executes ...
Gabriel Benoit   +4 more
openaire   +1 more source

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

open access: yesAdvanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma   +6 more
wiley   +1 more source

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

open access: yesAdvanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi   +4 more
wiley   +1 more source

Trapezoidal Generalization over Linear Constraints [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2018
We are developing a model-based fuzzing framework that employs mathematical models of system behavior to guide the fuzzing process. Whereas traditional fuzzing frameworks generate tests randomly, a model-based framework can deduce tests from a behavioral
David Greve, Andrew Gacek
doaj   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

open access: yesAdvanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando   +2 more
wiley   +1 more source

Grammar-aware test case trimming for efficient hybrid fuzzing

open access: yesJournal of King Saud University: Computer and Information Sciences
In recent years, hybrid fuzzing has garnered significant attention by combining the benefits of both fuzzing and concolic execution. However, existing hybrid fuzzing techniques face problems such as the performance overhead of concolic execution and low ...
Yiru Zhao, Long Gao, Qihan Wan, Lei Zhao
doaj   +1 more source

Research on Collision-Free Grey Box Fuzzing Method

open access: yes四川大学学报. 自然科学版, 2023
Grey-box fuzzing technology has been proved to be an efficient and practical vulnerability mining technology. It is widely used in the field of vulnerability mining, and many high-risk vulnerabilities are found through grey-box fuzzing.
WANG Song, FANG Yong, JIA Peng
doaj  

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

open access: yesAdvanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang   +8 more
wiley   +1 more source

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