Results 121 to 130 of about 15,044 (262)

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

open access: yesAdvanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia   +4 more
wiley   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

open access: yesAdvanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Multi‐Modal Low‐Power Adaptive Braille Recognition System Based on Hf0.3Zr0.7O2 Memristor

open access: yesAdvanced Science, EarlyView.
A multimodal adaptive perception system based on HZO ferroelectric memristor realizes efficient Braille digit recognition via reservoir computing. It delivers high recognition accuracy with ultralow‑energy analog computation, offering a promising hardware solution for environment‑robust neuromorphic assistive devices for visually impaired users ...
Jikang Xu   +9 more
wiley   +1 more source

Mechanophore‐Based Multichannel Colorimetric Force Sensors: Ultrasound‐Driven Stress and Strain Quantification

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mechanophores with mechanochromic properties have attracted significant attention as force‐responsive materials for structural sensing. However, their applications remain mainly limited to qualitative force visualization, as direct and quantitative extraction of mechanical parameters such as stress and strain from mechanochromic responses has ...
Seungo Baek   +8 more
wiley   +1 more source

Chemomechanically Adaptive MXene–Si–Ag Dual‐Seed Interlayer Enabling Low‐Pressure Sulfide all‐Solid‐State Batteries

open access: yesAdvanced Energy Materials, EarlyView.
Interfacial chemo‐mechanical instability limits stable operation of sulfide‐based all‐solid‐state batteries under low stack pressure. Here, a chemomechanically adaptive MXene–Si–Ag dual‐seed interlayer integrates immobile and mobile lithiophilic sites within a mechanically compliant MXene framework, regulating Li‐ion flux, stabilizing solid–solid ...
Youngjin Song   +7 more
wiley   +1 more source

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