Results 141 to 150 of about 710,451 (294)

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

open access: yesAdvanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka   +10 more
wiley   +1 more source

Water Supply Network in a Fuzzy Environment ; Maximum-Entropy Approach

open access: yes, 2015
[[abstract]]The maximum entropy principle initiated by Jaynes [5] is a powerful optimization technique of determining the distribution of random system in the case of partial or incomplete information or data available about the system [7,10,12,13].
Mazumder, S. K., Roy, T. K., Jana, P.
core  

Portfolio selection based on fuzzy cross-entropy

open access: yes, 2009
In this paper, the Kapur cross-entropy minimization model for portfolio selection problem is discussed under fuzzy environment, which minimizes the divergence of the fuzzy investment return from a priori one. First, three mathematical models are proposed
Qin, Zhongfeng, Ji, Xiaoyu, Li, Xiang
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

open access: yesAdvanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge   +13 more
wiley   +1 more source

Bounds on Two Parametric New Generalized Fuzzy Entropy [PDF]

open access: yes, 2016
In this paper we define a new two parametric generalized fuzzy average code-word length...Keywords Fuzzy set, Membership function, Shannon’s entropy, Fuzzy entropy, Code-word length, Kraft inequality, Coding theorem, Holder’s inequality and Optimal code ...
Bhat, Ashiq. Hussain   +2 more
core  

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

open access: yesAdvanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li   +6 more
wiley   +1 more source

Comparing Fuzzy-Rough and Fuzzy Entropy-assisted Fuzzy-Rough Feature Selection

open access: yes, 2008
Feature Selection (FS) methods based on fuzzy-rough set theory (FRFS) have employed the dependency function to guide the FS process with much success. More recently a method has been developed which uses fuzzy-entropy [9] to perform this task.

core  

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