Results 161 to 170 of about 1,831,408 (276)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

Denoise Stepwise Signals by Diffusion Model‐Based Approach

open access: yesSmall Methods, EarlyView.
This work presents SSDM, a diffusion‐model‐based framework for denoising stepwise signals in single‐molecule measurements. By learning the statistical structure of state transitions and noise, SSDM reconstructs signal levels and identifies transition time points more accurately than conventional approaches, enabling robust analysis of signals across ...
Xingdi Tong, Chenyu Wen
wiley   +1 more source

Dynamic Bayesian network-based risk assessment for gas treatment station. [PDF]

open access: yesSci Rep
Zerrouki H   +5 more
europepmc   +1 more source

Fuzzy Fault Tree Analysis and Its Applications

open access: yesJournal of Japan Society for Fuzzy Theory and Systems, 1993
Yasuhiro TSUJIMURA   +2 more
openaire   +2 more sources

A Novel Approach to Energy Management in Electric Steelworks

open access: yessteel research international, EarlyView.
Feed‐forward neural networks are exploited to estimate electric energy consumptions of the electric arc furnace and ladle furnace processes. The models are used to optimize production schedule so that more energy intensive grades are produced when the cost of energy is lower.
Valentina Colla   +12 more
wiley   +1 more source

Explainable Machine Learning for Predicting Time‐to‐Failure of Horizontal Pressurized Storage Tanks in Fire Scenarios

open access: yesSafety Science and Technology, EarlyView.
An interpretable machine learning framework with SHAP analysis achieves accurate time‐to‐failure prediction for horizontal pressurized tanks under pool fires while identifying fire intensity, filling level, and wall thickness as dominant drivers of model explanation and uncertainty explanation, providing transparent and actionable insights for ...
Yubin Mu   +5 more
wiley   +1 more source

Toward Enhanced Safety Management in Wave Energy Power Plant Construction Projects: FMEA and HAZOP Combination

open access: yesSafety Science and Technology, EarlyView.
Consolidated FMEA–HAZOP safety management framework for WEC construction projects. ABSTRACT This study presents an advanced safety management framework for “Wave Energy Converter” (WEC) projects, addressing the inherent uncertainty, technological complexity, and environmental exposure of offshore renewable energy systems.
Panagiotis K. Marhavilas   +4 more
wiley   +1 more source

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