Results 131 to 140 of about 25,079 (311)
Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Decentralized Control for Time-delay Nonlinear Interconnected Systems
工程科学与技术, 2011 :The decentralized state feedback control was studied for a kind of nonlinear interconnected systems with time-varying delay in both states and inputs.
GUO Gang +3 more
doaj
MathematicsThis paper investigates the problem of stability analysis for Takagi–Sugeno fuzzy systems with time-varying delays. By integrating an augmented delay-dependent Lyapunov–Krasovskii functional (LKF) structure, a refined LKF based on auxiliary function ...
Chang-Ho Lee +4 more
doaj +1 more source
Fuzzy autocatalytic set of fuzzy graph type-3 based on functional analysis theory [PDF]
, 2016 Fuzzy Autocatalytic Set (FACS) of fuzzy graph Type-3 is one of the newly capable graphs for a breakthrough of the relationship between fuzzy graph and autocatalytic set.
Qasim, Umilkeram
core
Ethical Precision in Nanoscale Brain Interfacing
Advanced Science, EarlyView.As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley +1 more source
Complex knowledge modelling with functional entity relationship diagrams
, 2011 Modelling complex knowledge resources can be problematical as there is currently no formalism that can represent the nature of the data-seeking process at a conceptual level.
Hobbs, V.J., Pigott, D.J.
core
Advanced Science, EarlyView.Here, we demonstrate and investigate polarization‐enabled electromechanical responses in cryogenic physical vapor deposition (cryogenic PVD)‐deposited TexSe1‐x thin films, a tellurium‐based compound with a tunable bandgap and enhanced non‐centrosymmetry.
Chia‐Chen Chung +16 more
wiley +1 more source
Análise de pontos por função fuzzy: modelo e resultados.
Revista Tecnologia, 2009 Function Point Analysis(FPA) is a largely used techniqueto estimate the size of development project, enhancemen ptroject or applications already installed.
Osias Souza Lima Júnior +2 more
doaj
Advanced Science, EarlyView.This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu +16 more
wiley +1 more source