Results 141 to 150 of about 15,918 (289)

Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan‐Degrader

ChemMedChem, EarlyView.
This study introduced DCAF11 as an E3 ligase for PROTAC‐mediated histone deacetylase (HDAC) degradation. By replacing cereblon with DCAF11 as recruited E3 ligase, a selective HDAC6 degrader (A6) was transformed into pan‐HDAC degraders. The lead compound, 1j (FF2039), potently degraded HDACs from classes I, IIa, and IIb, showing strong antiproliferative
Felix Feller, Heiko Weber, Martina Miranda, Irina Honin, Maria Hanl, Finn K. Hansen   +5 more
wiley   +1 more source

Benchmarking the performance of a low‐cost magnetic resonance control system at multiple sites in the open MaRCoS community

NMR in Biomedicine, Volume 36, Issue 1, January 2023., 2023
This article describes the current properties and capabilities of MaRCoS (Magnetic Resonance Control System), an open‐source console with the aim of providing an inexpensive yet flexible platform for low‐cost MRI. The results presented show that sequences commonly used in the clinic can be programmed into an open‐source system and already produce high ...
Teresa Guallart‐Naval, Thomas O'Reilly, José M. Algarín, Ruben Pellicer‐Guridi, Yolanda Vives‐Gilabert, Lincoln Craven‐Brightman, Vlad Negnevitsky, Benjamin Menküc, Fernando Galve, Jason P. Stockmann, Andrew Webb, Joseba Alonso   +11 more
wiley   +1 more source

Application of Edge Coloring of a Fuzzy Graph

, 2010
B. Poornima, V. Ramaswamy
openalex   +1 more source

On strongly edge irregular fuzzy graphs [PDF]

, 2016
N.R. Santhimaheswari, C. Sekar
openalex   +1 more source

Fuzzy Graph Structures: A Generalised Approach

, 2011
T. B. Dinesh, Ramakrishnan T.V.
openalex   +1 more source

Investigating the Anionic Redox Mechanism of Lithium Rich Cathodes

ChemNanoMat, EarlyView.
F‐doping of Li‐rich cathodes reveals that activation proceeds through a two‐step mechanism. The first step is a static reductive coupling mechanism that generates anionic redox and oxygen vacancies. These oxygen vacancies trigger the second step, a mobile TM‐migration mechanism.
Trent Seaby, Tongen Lin, Xia Huang, Lachlan Casey, Lianzhou Wang   +4 more
wiley   +1 more source

Methods for drug safety signal detection using routinely collected observational electronic health care data: A systematic review

Pharmacoepidemiology and Drug Safety, Volume 32, Issue 1, Page 28-43, January 2023., 2023
Abstract Purpose Signal detection is a crucial step in the discovery of post‐marketing adverse drug reactions. There is a growing interest in using routinely collected data to complement established spontaneous report analyses. This work aims to systematically review the methods for drug safety signal detection using routinely collected healthcare data
Astrid Coste, Angel Wong, Marleen Bokern, Andrew Bate, Ian J. Douglas   +4 more
wiley   +1 more source

On the Recognition of Fuzzy Circular Interval Graphs

, 2011
Gianpaolo Oriolo, Ugo Pietropaoli, Gautier Stauffer   +2 more
openalex   +2 more sources

Mining λ-Maximal Cliques from a Fuzzy Graph [PDF]

, 2016
Fei Hao, Doo-Soon Park, Shuai Li, HwaMin Lee�   +3 more
openalex   +1 more source

Assessing the Sustainable Transition in LSPs Industry

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The growing pressure on logistics service providers (LSPs) to achieve strong sustainability performance highlights the importance of aligning their practices with technological tools to support such endeavour. Given the significant effort required to implement sustainability measures in companies, it is crucial to focus on implementing these ...
Piera Centobelli
wiley   +1 more source