Results 81 to 90 of about 75,742 (295)

Probability-hesitant fuzzy sets and the representation of preference relations

open access: yesTechnological and Economic Development of Economy, 2018
Probability interpretations play an important role in understanding decision makers’ (DMs) behaviour in decision making. In this paper, we extend hesitant fuzzy sets to probability-hesitant fuzzy sets (P-HFSs) to enhance their modeling ability by taking ...
Bin Zhu, Zeshui Xu
doaj   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

open access: yesAdvanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong   +8 more
wiley   +1 more source

OWA-based fuzzy m-ary adjacency relations in Social Network Analysis. [PDF]

open access: yes
In this paper we propose an approach to Social Network Analysis (SNA) based on fuzzy m-ary adjacency relations. In particular, we show that the dimension of the analysis can naturally be increased and interesting results can be derived.
Mario Fedrizzi   +2 more
core  

Transitive matrices, strict preference and intensity operators [PDF]

open access: yes, 2006
Let X be a set of alternatives and a_{ij} a positive number expressing how much the alternative x_{i} is preferred to the alternative x_{j}. Under suitable hypothesis of no indifference and transitivity over the pairwise comparison matrix A= (a_{ij}),
BASILE, LUCIANO, D'APUZZO, LIVIA
core  

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

On fuzzy non-discrimination [PDF]

open access: yes
We show that the incompatibility between the Pareto principle and the notion of non-discrimination as presented in Xu (2000) continues to hold when the individuals have exact preferences and the social preference relation is allowed to be a reflexive and
Dinko Dimitrov
core  

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

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