Results 81 to 90 of about 7,153 (275)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Cyber security challenges for software vendors through a fuzzy-TOPSIS approach [PDF]

PeerJ Computer Science
Cyber security has become a critical part of computer systems and recent technological developments have focused on making production and distribution processes more fluid and efficient. The introduction of Industry 4.0 and its significant impact on life
Abdullah M. Alnajim, Abdul Wahid Khan, Shah Zaib, Shabbab Algamdi, Faheem Khan   +4 more
doaj   +2 more sources

Study of Free‐Space Optical Quantum Network: Review and Prospectives

Advanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

Fuzzy Quasi-Ideals of Ordered Semigroups [PDF]

, 2011
. In this paper, we characterize ordered semigroups in terms of fuzzy quasi-ideals. We characterize left simple, right simple and completely regular ordered semigroups in terms of fuzzy quasi-ideals.
Muhammad Shabir, Asghar Khan
core   +1 more source

Fully fuzzy prime semigroups

, 2020
We characterize those semigroups for which each fuzzy ideal is prime.
M Shabir
core  

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

PENGGUNAAN BEBERAPA JENIS BATASAN TITIK IDEAL POSITIF DAN NEGATIF PADA METODE FUZZY TOPSIS [PDF]

, 2019
Pada metode Fuzzy Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) terdapat beberapa tipe Fuzzy Positive Ideal Solution (FPIS) dan Fuzzy Negative Ideal Solution (FNIS) yang digunakan.
GUNTUNG PRIAMBADA, 081511633026
core  

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

SISTEM PENDUKUNG KEPUTUSAN PEMILIHAN PERGURUAN TINGGI SWASTA MENGGUNAKAN TOPSIS

Jurnal Riset Informatika, 2019
Choosing the right college is a crucial step for students in preparing for their careers and future. With education at the college, the student increases their chances of getting better jobs.
Tati Mardiana, Siska Selvia Tanjung
doaj   +1 more source