Results 131 to 140 of about 16,303 (230)

Regulation of FVIII-specific immunity in Hemophilia A mice

The major complication of Hemophilia A treatment is the formation of inhibitors that neutralize the administered FVIII. Immune tolerance induction (ITI) is the most frequently used therapy in order to establish long-lasting tolerance towards FVIII in ...
Jurado Mestre, Blanca
core   +1 more source

Discovery and development of a bispecific antibody for the treatment of hemophilia. [PDF]

Proc Natl Acad Sci U S A
Pao W.
europepmc   +1 more source

Kunihiro Hattori, Tomoyuki Igawa, and Takehisa Kitazawa share Lasker Award honors for revolutionary hemophilia A therapy. [PDF]

J Clin Invest
Flaumenhaft R.
europepmc   +1 more source

A Novel Complete F8 Tandem Duplication Causing Elevated Factor VIII Activity and Associated with Venous Thromboembolism. [PDF]

TH Open
Mao Y, Lu Y, Wu W, Ding Q, Wang X, Dai J, Wu X.   +6 more
europepmc   +1 more source

Tissue Factor/Factor XIa Dual-activated Thrombin Generation is Able to Reliably Measure Thrombin Generation at All Hemophilia A Disease Severities. [PDF]

TH Open
van de Berg TW, Heinzmann A, Thomassen S, Schols SEM, Heubel-Moenen FCJI, van Es N, Rosendaal FR, Gouw S, Hackeng TM, Beckers EAM.   +9 more
europepmc   +1 more source

Structural basis for membrane binding by coagulation factors V and VIII and their specificity for phosphatidylserine-containing membranes. [PDF]

Proc Natl Acad Sci U S A
Kolyadko VN, Pumroy RA, Moiseenkova-Bell VY, Krishnaswamy S.   +3 more
europepmc   +1 more source

Plasma emicizumab concentrations and bleeding rates in children and adults with severe hemophilia A. [PDF]

Res Pract Thromb Haemost
Teitel J, Carcao M, Sholzberg M, Thillaye-Kerr R, Swarup V, Markovic T, Bouskill V.   +6 more
europepmc   +1 more source

Maternal microchimerism accelerates immune tolerance induction to factor VIII in children with hemophilia A and FVIII inhibitors. [PDF]

Front Immunol
Li Z, Lu Y, Chen Z, Dai J, Wu X, Cai X, Pan X, Cai S, Li G, Cheng X, Ai D, Zhang J, Ding Q, Wu W, Wang X, Wu R.   +15 more
europepmc   +1 more source

Acquired hemophilia a caused by complicated urinary tract infection due to flavobacterium odoratum: A case report and literature review. [PDF]

Medicine (Baltimore)
Chen D, Yuan P, Ren M.
europepmc   +1 more source

Bestimmung der Immunogenität verschiedener FVIII-Moleküle in einem FVIII toleranten präklinischen Mausmodell, anhand der Balance zwischen FVIII-spezifischen Treg und Teff Zellen

, 2013
Die heutige Standardversorgung für Patienten mit der Blutgerinnungsstörung Hämophilie A umfasst eine rekombinante Proteinersatztherapie des fehlenden oder defekten Faktor VIII (FVIII).
Weyrer, Franziska
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