Results 1 to 10 of about 2,807 (196)
Sulforaphane as a potential therapeutic agent: a comprehensive analysis of clinical trials and mechanistic insights. [PDF]
J Nutr SciSaito A +4 more
europepmc +1 more source
Meeting Abstracts of the 1st Fragile X International Congress. [PDF]
Orphanet J Rare Diseuropepmc +1 more source
FXTAS presents with upregulation of the cytokines IL12 and TNFα [PDF]
Parkinsonism and Related Disorders, 2021 Fragile X Tremor and Ataxia Syndrome is a progressive neurodegenerative disorder that develops in some FMR1 premutation carriers. The objective of this study is to characterize how cytokine levels are altered in the FXTAS brain.Fresh frozen cerebellar tissue from FXTAS cases and controls was homogenized and analyzed for 12 different cytokines using a ...
Brett D Dufour +1 more
exaly +7 more sources
Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS): A Gender Perspective
Journal of Clinical Medicine, 2022 Although larger trinucleotide expansions give rise to a neurodevelopmental disorder called fragile X syndrome, fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder caused by a “premutation” (55&ndash ...
Daniele Orsucci +2 more
exaly +2 more sources
Blood Proteome Profiling Reveals Biomarkers and Pathway Alterations in Fragile X PM at Risk for Developing FXTAS [PDF]
International Journal of Molecular Sciences, 2023 Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder associated with the FMR1 premutation. Currently, it is not possible to determine when and if individual premutation carriers will develop FXTAS.
Marwa Zafarullah +2 more
exaly +2 more sources
The emerging molecular mechanisms for mitochondrial dysfunctions in FXTAS
Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2020 Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inherited neurodegenerative disorder caused by an expansion of 55-200 CGG repeats at 5UTR of FMR1 gene, known as premutation. The main clinical and neuropathological features of FXTAS include progressive intention tremor, gait ataxia, neuronal cell loss and presence of ubiquitin-positive ...
Dhruv Gohel +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.
Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS): Pathophysiology and Clinical Implications
International Journal of Molecular Sciences, 2020Ana Maria Cabal-Herrera +2 more
exaly
Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS)
Brain, 2006Claudia M Greco, Jim Grigsby
exaly