Results 61 to 70 of about 103,546 (246)

MSKE and Z-FY-CHO inhibit cell migration and invasion.

open access: yes, 2019
(A) Migration on collagen and (B) Invasion on matrigel was performed using a boyden chamber with or without treatment of MDA-MB-468 or MDA-MB-231 cells with MSKE or Z-FY-CHO. Graphical data represents three independent experiments * means 0.05 > p value >
Liza J. Burton (615553)   +5 more
core   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

open access: yesAdvanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao   +9 more
wiley   +1 more source

Dynamic Etching‐Induced Cl‐Terminated Ti3C2Clx/Ti3ZnC2 Heterostructure for Ammonia Electrosynthesis and Zinc‐Nitrogen Batteries

open access: yesAdvanced Science, EarlyView.
A stable Ti3C2Clx/Ti3ZnC2 heterostructure, fabricated by dynamic etching, exhibits outstanding electrocatalytic NRR activity (NH3 yield: 20.1 µg h−1 mg−1, FE: 38.1%) in alkaline media. The corresponding Zn‐N2 battery achieves a peak power density of 36.5 µW cm−2 and an NH3 yield of 13.1 µg h−1 mg−1, providing an advanced strategy for NH3 and ...
Yu Wang   +9 more
wiley   +1 more source

Daily multi-time monitoring of SLST jointly using FY-3 dawn-dusk and afternoon orbit satellite data with 250 m resolution

open access: yesInternational Journal of Digital Earth
Snow/land surface temperature (SLST) has a significant impact on snow melting, metamorphism, and land-atmosphere energy exchange. It is also an important factor that affects outdoor skiing during the Olympic Winter Games (OWG).
Lixin Dong   +4 more
doaj   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

open access: yesAdvanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong   +12 more
wiley   +1 more source

A Smart Fluid‐Hydraulic System Based on MRF Valve Control and Its Application in Flexible Grasping

open access: yesAdvanced Science, EarlyView.
This study introduces a smart fluid hydraulic system using MRF valve control for flexible gripping. An MRF‐MSV with an integrated excitation coil and micro‐textured damping channels is designed and validated; micro‐texturing increases hydraulic resistance. Coupled with a soft actuator, the MRF‐MSV enables dynamic bending and grasping.
Linfeng Huo   +5 more
wiley   +1 more source

Lightweight, Elastic Ceramic Fabrics for Broadband Electromagnetic Absorption and High Temperature Thermal Insulation

open access: yesAdvanced Science, EarlyView.
This study reports lightweight, elastic ceramic fabrics with broadband electromagnetic absorption (EAB = 9.8 GHz) and high‐temperature thermal insulation, enabled by precise microstructural control during ultrafast high‐temperature sintering (UHS), which induces the precipitation of defect‐rich t‐ZrO2 nanograins and turbostratic C nanoclusters.
Jiahao Yang   +9 more
wiley   +1 more source

Land surface temperature retrieval from FY-3E/MERSI using an optimized water vapor scaling method

open access: yesGIScience & Remote Sensing
This paper presents a new temperature and emissivity separation (TES) algorithm for retrieving land surface temperature (LST) from the MEdium Resolution Spectral Imager-LL (MERSI) onboard Fengyun-3E (FY-3E), the first satellite of the FY-3 series placed ...
Weihan Liu, Jie Cheng, Lixin Dong
doaj   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

open access: yesAdvanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu   +11 more
wiley   +1 more source

Targeted Multifunctional Fluorine‐Rich Copolymer Coating Design for Ambient‐Stable Prelithiated SiOC Anodes

open access: yesAdvanced Science, EarlyView.
A fluorine‐rich acrylate copolymer, poly (tridecafluorooctyl methacrylate‐co‐methyl methacrylate) (PFMMA), is introduced as a multifunctional protective coating to stabilize the prelithiated SiOC electrodes in humid conditions and preserve unimpeded interfacial ion/charge transport during redox reactions.
Rong Chen   +10 more
wiley   +1 more source

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