Results 1 to 10 of about 276,085 (274)

Inconsistent approaches of the G-BA regarding acceptance of primary study endpoints as being relevant to patients - an analysis of three disease areas: oncological, metabolic, and infectious diseases [PDF]

BMC Health Services Research, 2016
Background Previous evaluations of oncological medicines in the German early benefit assessment (EBA) procedure have demonstrated inconsistent acceptance of endpoints by regulatory authorities and the Federal Joint Committee (G-BA).
Thomas Staab, Georg Isbary, Volker E. Amelung, Jörg Ruof   +3 more
doaj   +2 more sources

Neugebauer: „Aus unserer Sicht innovationsfeindlich“

Monitor Versorgungsforschung, 2022
Am 27. Juli 2022 hat das Bundeskabinett den Entwurf eines Gesetzes zur finanziellen Stabilisierung der gesetzlichen Krankenversicherung (GKV-Finanzstabilisierungsgesetz) beschlossen, der – nachdem ins parlamentarische Verfahren eingebracht – am 20 ...
Peter Stegmaier
doaj   +1 more source

Suche nach dem Versorgungsforschungs-Impact

Monitor Versorgungsforschung, 2022
Es ist eine reine Fleißaufgabe, sich der Frage zu nähern, wie viele der vom Innovationsfonds geförderten und inzwischen vom Innovationsausschuss mit Beschluss beendeten Versorgungsforschungsprojekte „positiv“ oder „negativ“ beschieden wurden, da der G-BA
Peter Stegmaier
doaj   +1 more source

Auswirkungen der neuen Dossieranforderungen

Monitor Versorgungsforschung, 2023
Bei Markteintritt oder Zulassungserweiterung eines neuen Arzneimittels sind pharmazeutische Unternehmer in Deutschland seit 2011 zur Einreichung eines AMNOG-Nutzendossiers beim G-BA verpflichtet.
Dr. rer. nat. Maria Katharina Schweitzer, Dr. rer. nat. Manuel Nico Dold, Dr. rer. nat. Astrid Genet, Klaus Gossens PhD, Dipl.-Math. Thomas Klein-Hessling, Nils Löffler MSc, Dr. phil. Matthias Rabel, Dr. PH Andrej Rasch, Jessica Schmelcher MSc, Dr. rer. nat. Sebastian Werner, Natalia Wolfram   +10 more
doaj   +1 more source

Optimization of an In Vitro Embryo Rescue Protocol for Breeding Seedless Table Grapes (Vitis vinifera L.) in Italy

Horticulturae, 2022
Conventional crossing of stenospermocarpic grapes for the obtainment of seedless cultivars presents some technical constraints causing embryo abortion in the early berry developmental stages. Embryo rescue technique partially overcomes these limitations,
Angelica Giancaspro, Andrea Mazzeo, Antonio Carlomagno, Agata Gadaleta, Stefano Somma, Giuseppe Ferrara   +5 more
doaj   +1 more source

„Scientists make decisions, policy makers take decisions“

Monitor Versorgungsforschung, 2022
Prof. Dr. Franz Porzsolt, der seit dem Jahr 1994 in vielen wissenschaftlichen Publikationen seinen Begriff von klinischer Ökonomik zu prägen versucht und zudem als einer der Erfinder der „Pragmatic Controlled Trials“ gelten kann, gilt ebenso als ein eher
Prof. Dr. med. Franz Porzsolt, Peter Stegmaier   +1 more
doaj   +1 more source

Glycosylated Zein Composite Nanoparticles for Efficient Delivery of Betulinic Acid: Fabrication, Characterization, and In Vitro Release Properties

Foods, 2022
Betulinic acid (BA) has anti-inflammatory, antioxidative stress, and antitumor activities, but BA bioavailability is low due to its poor water solubility and short half-life.
Fei Peng, Yu Jin, Kunhua Wang, Xiaojing Wang, Yaqing Xiao, Huaide Xu   +5 more
doaj   +1 more source

Effects of the availability of new oral anticoagulants in patients with non-valvular atrial fibrillation in the real world: the NAIF study

Italian Journal of Medicine, 2016
Guidelines recommend anticoagulation to prevent stroke in patients with non-valvular atrial fibrillation (NVAF). In the real world, this treatment is underused, probably for pharmacologic limitations of vitamin-K-antagonist (VKA).
Francesco Ventrella, Franco Mastroianni, Sergio Cappello, Luigi Iamele, Samantha Errico, Massimo Errico   +5 more
doaj   +1 more source

Benzoic Acid Combined with Essential Oils Can Be an Alternative to the Use of Antibiotic Growth Promoters for Piglets Challenged with E. coli F4

Animals, 2020
Benzoic acid (BA) and essential oils (EOs) (thymol, 2-methoxyphenol, eugenol, piperine, and curcumin) are being studied to minimize the impairment of gastrointestinal functions in weanling piglets.
Leticia Mendonça Rodrigues, Túlio Otávio de Araújo Lima Neto, Cesar Augusto Pospissil Garbossa, Claudia Cassimira da Silva Martins, Dino Garcez, Laya Kannan Silva Alves, Márvio Lobão Teixeira de Abreu, Rony Antonio Ferreira, Vinícius de Souza Cantarelli   +8 more
doaj   +1 more source

Biogenic amines content in Fiore Sardo cheese in relation to free amino acids and physicochemical characteristics

Italian Journal of Food Safety, 2020
Fiore Sardo is a Protected Designation of Origin (PDO) cheese produced in Sardinia (Italy) from raw sheep’s milk, presenting risk factors due to an accumulation of Biogenic Amines (BA).
Gavina Manca, Antonio Ru, Giuliana Siddi, Anna Maria Mocci, Gavino Murittu, Enrico Pietro Luigi De Santis   +5 more
doaj   +1 more source