Results 21 to 30 of about 263,600 (280)

Kein Zusatznutzen aus formalen Gründen

Monitor Versorgungsforschung
„Fernab der Versorgungsrealität und ohne Berücksichtigung der Expertenmeinungen führender Fachgesellschaften”, lautet das Fazit von Johnson & Johnson zu dem Beschluss des Gemeinsamen Bundesausschusses (G-BA), der am 18.
Peter Stegmaier
doaj   +1 more source

Single nucleotide variants of filaggrin and glucocorticoid receptors genes in children suffering different phenotypes of atopic diseases

Medičnì Perspektivi, 2022
Currently, there is an apparent need for genotype-associated personalization of the diagnostic process for atopic diseases (AtD) in children: atopic dermatitis (AD), seasonal allergic rhinitis (conjunctivitis – (SAR(C)), perennial allergic rhinitis ...
V.O. Dityatkovsky , N.V. Naumenko , О.O. Alifirenko, N.L. Pinaeva , S.T. Taran , I.A. Filatova, O.Ye. Abaturov   +6 more
doaj   +1 more source

„Ein stimmiges Konzept für systematischen Transfer“

Monitor Versorgungsforschung
„Nur so können wir die nötige Evidenz schaffen, die man für jede Art von Verbesserung des Systems dringend benötigt” (Hoffmann). „Transfer darf nicht nur vom guten Willen der Beteiligten abhängen” (Hecken).
Prof. Dr. med. Wolfgang Hoffmann MPH, Prof. Josef Hecken, Prof. Dr. Reinhold Roski, Peter Stegmaier   +3 more
doaj   +1 more source

Biohydrogen Fermentation from Sucrose and Piggery Waste with High Levels of Bicarbonate Alkalinity

Energies, 2015
This study examined the influence of biohydrogen fermentation under the high bicarbonate alkalinity (BA) and pH to optimize these critical parameters. When sucrose was used as a substrate, hydrogen was produced over a wide range of pH values (5–9) under ...
Jeongdong Choi, Youngho Ahn
doaj   +1 more source

Characterizing indigenous plant growth promoting bacteria and their synergistic effects with organic and chemical fertilizers on wheat (Triticum aestivum)

Frontiers in Plant Science, 2023
The excessive use of chemical fertilizers is deteriorating both the environment and soil, making it a big challenge faced by sustainable agriculture. To assist the efforts for the solution of this burning issue, nine different potential native strains of
Israr Asghar, Maqsood Ahmed, Muhammad Ansar Farooq, Muhammad Ishtiaq, Muhammad Arshad, Muhammad Akram, Adnan Umair, Abdulwahed Fahad Alrefaei, Muhammad Yousuf Jat Baloch, Aamna Naeem   +9 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Urinary Elimination of Bile Acid Glucuronides under Severe Cholestatic Situations: Contribution of Hepatic and Renal Glucuronidation Reactions

Canadian Journal of Gastroenterology and Hepatology, 2018
Biliary obstruction, a severe cholestatic complication, causes accumulation of toxic bile acids (BAs) in liver cells. Glucuronidation, catalyzed by UDP-glucuronosyltransferase (UGT) enzymes, detoxifies cholestatic BAs. Using liquid chromatography coupled
Martin Perreault, Ewa Wunsch, Andrzej Białek, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Guy G. Poirier, Piotr Milkiewicz, Olivier Barbier   +8 more
doaj   +1 more source

Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction. [PDF]

PLoS ONE, 2013
Biliary obstruction, a severe cholestatic condition, results in a huge accumulation of toxic bile acids (BA) in the liver. Glucuronidation, a conjugation reaction, is thought to protect the liver by both reducing hepatic BA toxicity and increasing their ...
Martin Perreault, Andrzej Białek, Jocelyn Trottier, Mélanie Verreault, Patrick Caron, Piotr Milkiewicz, Olivier Barbier   +6 more
doaj   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source